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Case Report: Primary Squamous Cell Carcinoma of a Tarsal Bone

We describe a rare case of primary squamous cell carcinoma of the cuneiform bone of the foot in a 57-year-old man. In the appendicular skeleton, epithelial carcinomas of bone are usually metastatic deposits, primary squamous cell carcinomas of bone being found more frequently in the skull. A review...

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Bibliographic Details
Published in:Clinical orthopaedics and related research 2009-12, Vol.467 (12), p.3346-3350
Main Authors: Gaston, Czar Louie L., Vergel de Dios, Ariel M., Dela Rosa, Tammy L., Wang, Edward H. M.
Format: Article
Language:English
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Summary:We describe a rare case of primary squamous cell carcinoma of the cuneiform bone of the foot in a 57-year-old man. In the appendicular skeleton, epithelial carcinomas of bone are usually metastatic deposits, primary squamous cell carcinomas of bone being found more frequently in the skull. A review of the English literature revealed only two other reported cases of primary squamous cell carcinoma outside the skull—one in the ilium and one in the tibia. In our patient, extensive metastatic workup and monitoring during more than 2 years showed no primary focus, supporting the rare presentation of a primary squamous cell carcinoma of bone in the appendicular skeleton.
ISSN:0009-921X
1528-1132
DOI:10.1007/s11999-009-0926-3