Effect of mucin production on survival in colorectal cancer: a case-control study

To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage. Thirty five pati...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2008-12, Vol.14 (45), p.6981-6985
Main Authors: Farhat, Mirna H, Barada, Kassem A, Tawil, Ayman N, Itani, Doha M, Hatoum, Hassan A, Shamseddine, Ali I
Format: Article
Language:English
Subjects:
Adenocarcinoma - metabolism
Adenocarcinoma - mortality
Adenocarcinoma - therapy
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor - metabolism
Case-Control Studies
Colorectal Neoplasms - metabolism
Colorectal Neoplasms - mortality
Colorectal Neoplasms - therapy
Combined Modality Therapy
Disease Progression
Female
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Mucins - metabolism
Rapid Communication
Retrospective Studies
Survival Rate
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Summary:To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage. Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls (
ISSN:1007-9327
DOI:10.3748/wjg.14.6981