Assessment of obstruction length and optimal viewing angle from biplane X-ray angiograms

• Published in: The International Journal of Cardiovascular Imaging 2010-01, Vol.26 (1), p.5-17
• Main Authors: Tu, Shengxian, Koning, Gerhard, Jukema, Wouter, Reiber, Johan H. C.
• Format: Article
• Language: English
• Subjects: Cardiac Imaging; Cardiology; Coronary Angiography - instrumentation; Coronary Angiography - methods; Coronary Stenosis - diagnostic imaging; Humans; Imaging; Imaging, Three-Dimensional; Medicine; Medicine & Public Health; Original Paper; Phantoms, Imaging; Predictive Value of Tests; Radiographic Image Interpretation, Computer-Assisted; Radiology; Reproducibility of Results; Tomography, X-Ray Computed - instrumentation
• ISSN: 1569-5794; 1573-0743; 1875-8312
• DOI: 10.1007/s10554-009-9509-3

Three-dimensional quantitative coronary angiography (3D QCA) has been encouraged by the increasing need to better assess vessel dimensions and geometry for interventional purposes. A novel 3D QCA system based on biplane X-ray angiograms is presented in this paper. By correcting for the isocenter offset and by improving the epipolar constraint for corresponding two angiographic projections, accurate and robust reconstruction of the vessel centerline is achieved and the reproducibility of its applications, e.g., the assessments of obstruction length and optimal viewing angle, is guaranteed. The accuracy and variability in assessing the obstruction length and optimal bifurcation viewing angle were investigated by using phantom experiments. The segment length assessed by 3D QCA correlated well with the true wire segment length ( r 2  = 0.999) and the accuracy and precision were 0.04 ± 0.25 mm ( P