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Wall Teichoic Acid Function, Biosynthesis, and Inhibition
Off the wall: Wall teichoic acids (WTAs) are negatively charged glycopolymers found in dense arrays on the surface of Gram‐positive bacteria. WTAs have profound effects on the physiology of Gram‐positive organisms, and impact everything from cation homeostasis to antibiotic susceptibility to surviva...
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| Published in: | Chembiochem : a European journal of chemical biology 2010-01, Vol.11 (1), p.35-45 |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c5677-941d1a38590dc2066fc746c35e061b94e8ca794fa1d4f410d322ec1b150aed973 |
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| cites | cdi_FETCH-LOGICAL-c5677-941d1a38590dc2066fc746c35e061b94e8ca794fa1d4f410d322ec1b150aed973 |
| container_end_page | 45 |
| container_issue | 1 |
| container_start_page | 35 |
| container_title | Chembiochem : a European journal of chemical biology |
| container_volume | 11 |
| creator | Swoboda, Jonathan G Campbell, Jennifer Meredith, Timothy C Walker, Suzanne |
| description | Off the wall: Wall teichoic acids (WTAs) are negatively charged glycopolymers found in dense arrays on the surface of Gram‐positive bacteria. WTAs have profound effects on the physiology of Gram‐positive organisms, and impact everything from cation homeostasis to antibiotic susceptibility to survival in a host. This review summarizes recent advances made toward understanding WTA function, biosynthesis and inhibition. |
| doi_str_mv | 10.1002/cbic.200900557 |
| format | article |
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| identifier | ISSN: 1439-4227 |
| ispartof | Chembiochem : a European journal of chemical biology, 2010-01, Vol.11 (1), p.35-45 |
| issn | 1439-4227 1439-7633 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2798926 |
| source | Wiley |
| subjects | Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology antibiotics biosynthesis conditionally essential enzymes Enzymes - metabolism Glycerophosphates - biosynthesis Glycerophosphates - chemistry Gram-positive bacteria Gram-Positive Bacteria - chemistry Gram-Positive Bacteria - enzymology Gram-Positive Bacteria - genetics Multigene Family Peptidoglycan - biosynthesis Peptidoglycan - chemistry Polysaccharides - biosynthesis Polysaccharides - chemistry Teichoic Acids - biosynthesis Teichoic Acids - chemistry wall teichoic acid (WTA) |
| title | Wall Teichoic Acid Function, Biosynthesis, and Inhibition |
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