Neuropsychiatric manifestation of confusional psychosis due to Cryptococcus neoformans var. grubii in an apparently immunocompetent host: a case report

Cognitive disorders like dementia, delirium, depression, anxiety, psychosis and mania are the commonest neuropsychiatric manifestations. We discuss here a case of an adult women presenting with neuropsychiatric manifestations of confusional psychosis owing to Cryptococcosis. The principal cause was...

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Bibliographic Details
Published in:Cases journal 2009-11, Vol.2 (1), p.9084-9084, Article 9084
Main Authors: Prakash, Peralam Yegneswaran, Sugandhi, Rao P
Format: Article
Language:English
Subjects:
Care and treatment
Case Report
Case studies
Cryptococcus
Diagnosis
Health aspects
Immunocompetent cells
Mental illness
Patient outcomes
Risk factors
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Summary:Cognitive disorders like dementia, delirium, depression, anxiety, psychosis and mania are the commonest neuropsychiatric manifestations. We discuss here a case of an adult women presenting with neuropsychiatric manifestations of confusional psychosis owing to Cryptococcosis. The principal cause was consequently established by culturing Cryptococcus neoformans from the cerebrospinal fluid confirmed as C. neoformans var. grubii (Serotype A) by genotypic methods. Antifungal therapy with IV Amphotericin B lead to sustained improvement and recovery of the patient from behavioural disorders. The case discussed here invokes the need for the vigilance it demands in delineating organic brain syndromes for a favourable treatment outcome.
ISSN:1757-1626
1757-1626
DOI:10.1186/1757-1626-2-9084