HBV genotype C is independently associated with cirrhosis in community-based population

AIM:To determine the association of hepatitis B virus (HBV) genotypes with probable cirrhosis and fatty liver in community-based populations.METHODS: A multi-stage cluster probability sampling method was applied to recruit 10 167 subjects aged between 6 and 72 years from our epidemiological bases in...

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Published in:World journal of gastroenterology : WJG 2010-01, Vol.16 (3), p.379-383
Main Authors: Yin, Jian-Hua, Zhao, Jun, Zhang, Hong-Wei, Xie, Jia-Xin, Li, Wei-Ping, Xu, Guo-Zhang, Shen, Jie, Dong, Hong-Jun, Zhang, Jun, Wang, Lin, Han, Jian-Kang, Wang, Hong-Yang, Cao, Guang-Wen
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Alanine Transaminase - blood
Brief
Child
China
Cluster Analysis
Community-Based Participatory Research
Fatty Liver - epidemiology
Fatty Liver - ethnology
Fatty Liver - virology
Female
Genotype
Hepatitis B e Antigens - blood
Hepatitis B virus - genetics
Humans
Liver - diagnostic imaging
Liver Cirrhosis - epidemiology
Liver Cirrhosis - ethnology
Liver Cirrhosis - virology
Male
Middle Aged
Multivariate Analysis
Prevalence
Retrospective Studies
Ultrasonography
Viral Load - genetics
Young Adult
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Summary:AIM:To determine the association of hepatitis B virus (HBV) genotypes with probable cirrhosis and fatty liver in community-based populations.METHODS: A multi-stage cluster probability sampling method was applied to recruit 10 167 subjects aged between 6 and 72 years from our epidemiological bases in Eastern China. After excluding the subjects co-infected with hepatitis C or hepatitis D viruses, the hepatitis B surface antigen (HBsAg)-positive subjects were examined for HBV genotype, serum viral load, alanin...
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v16.i3.379