Seroprevalence of IgG antibodies to the chlamydia-like microorganism ‘Simkania Z’ by ELISA

The newly described microorganism ‘Simkania Z’, related to the Chlamydiae, has been shown to be associated with bronchiolitis in infants and community acquired pneumonia in adults. The prevalence of infection in the general population is unknown. A simple ELISA assay for the detection of serum IgG a...

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Bibliographic Details
Published in:Epidemiology and infection 1999-02, Vol.122 (1), p.117-123
Main Authors: FRIEDMAN, M. G., GALIL, A., GREENBERG, S., KAHANE, S.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Antibodies
Antibodies, Bacterial - blood
Antigens
Bacteriology
Biological and medical sciences
Blood donation
Bronchiolitis - microbiology
Chlamydia
Chlamydia trachomatis
Chlamydia trachomatis - immunology
Chlamydiales - classification
Chlamydiales - immunology
Chlamydophila pneumoniae
Chlamydophila pneumoniae - immunology
Community-Acquired Infections - microbiology
Enzyme linked immunosorbent assay
Epidemiology
Female
Fundamental and applied biological sciences. Psychology
Gram-Negative Bacterial Infections - blood
Gram-Negative Bacterial Infections - epidemiology
Gram-Negative Bacterial Infections - immunology
Gram-Negative Bacterial Infections - microbiology
Humans
Immunoglobulin G - blood
Infections
Israel - epidemiology
Kibbutz
Male
Microbiology
Microorganisms
Pneumonia - microbiology
Seroepidemiologic Studies
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Summary:The newly described microorganism ‘Simkania Z’, related to the Chlamydiae, has been shown to be associated with bronchiolitis in infants and community acquired pneumonia in adults. The prevalence of infection in the general population is unknown. A simple ELISA assay for the detection of serum IgG antibodies to ‘Simkania Z’ was used to determine the prevalence of such antibodies in several population samples in southern Israel (the Negev). The groups tested included 94 medical and nursing students, 100 unselected blood donors, 106 adult members of a Negev kibbutz (communal agricultural settlement), and 45 adult Bedouin, residents of the Negev. IgG antibodies to ‘Simkania Z’ were found in 55–80% of these presumably healthy individuals, independently of antibodies to Chlamydia trachomatis and Chlamydia pneumoniae. The Bedouin had a seropositivity rate of 80%, while all other groups had rates of between 55 and 64%. These results indicate that ‘Simkania Z’ infection is probably common in southern Israel.
ISSN:0950-2688
1469-4409
DOI:10.1017/S095026889800185X