Nature or nurture; BMI and blood pressure at 90. Findings from the Belfast Elderly Longitudinal Free-living Aging STudy (BELFAST)

Hypertension is a key risk factor for stroke, cardiovascular disease and dementia. Although the link between weight, sodium and hypertension is established in younger people, little is known about their inter-relationship in people beyond 80 years of age. Associations between blood pressure, anthrop...

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Bibliographic Details
Published in:AGE 2009-12, Vol.31 (4), p.261-267
Main Authors: Rea, I. Maeve, Myint, Phyo K, Mueller, Heiko, Murphy, Anne, Archbold, G. Pooler R, McNulty, Helene, Patterson, Chris C
Format: Article
Language:English
Subjects:
Aged, 80 and over
Aging
Aging - physiology
Biomedical and Life Sciences
Blood pressure
Blood Pressure - physiology
Body Mass Index
Cell Biology
Cross-Sectional Studies
Disease Progression
Female
Geriatrics/Gerontology
Humans
Hypertension
Hypertension - epidemiology
Hypertension - etiology
Hypertension - physiopathology
Incidence
Ireland - epidemiology
Life Sciences
Male
Molecular Medicine
Odds Ratio
Pharmacists
Reference Values
Risk Factors
Smoking - adverse effects
Sodium - blood
Studies
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Summary:Hypertension is a key risk factor for stroke, cardiovascular disease and dementia. Although the link between weight, sodium and hypertension is established in younger people, little is known about their inter-relationship in people beyond 80 years of age. Associations between blood pressure, anthropometric indices and sodium were investigated in 495 apparently healthy, community-living participants (age 90, SD 4.8; range 80-106), from the cross-sectional Belfast Elderly Longitudinal Free-living Aging STudy (BELFAST) study. In age-sex-adjusted logistic regression models, blood pressure ≥140/90 mmHg significantly associated with body mass index (BMI) [odds ratio (OR) = 1.28/ kg/m²], with weight (OR = 1.22/kg) approaching significance (P = 0.07). In further age-sex-adjusted models, blood pressure above the 120/80 mmHg normotensive reference value significantly associated with BMI (OR = 1.44/kg/m²), weight (OR = 1.36/kg), skin-fold-thickness (OR = 1.33/mm) and serum sodium (OR = 1.37 mmol/l). In BELFAST participants over 80 years old, blood pressure ≥140/90 mmHg is associated with BMI, in apparently similar ways to younger groups.
ISSN:0161-9152
2509-2715
2331-3765
1574-4647
2509-2723
DOI:10.1007/s11357-009-9096-1