Primary mixed germ cell tumor of the liver with sarcomatous components

Germ cell tumor(GCT)of the liver is extremely rare. Here,we describe a case of hepatic mixed GCT with significant sarcomatous components and elevated serum α-fetoprotein(AFP)in a 34-year-old man.Histopathologically,the tumor was composed of two GCTs components:yolk sac tumor and immature teratoma.Th...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2010-02, Vol.16 (5), p.652-656
Main Authors: Xu, Ai-Min, Gong, Shao-Juan, Song, Wei-Hua, Li, Xiao-Wei, Pan, Chun-Hua, Zhu, Jun-Jun, Wu, Meng-Chao
Format: Article
Language:English
Subjects:
Adult
alpha-Fetoproteins - metabolism
Biomarkers, Tumor - blood
Case Report
Fatal Outcome
Humans
Liver Neoplasms - blood
Liver Neoplasms - pathology
Male
Neoplasms, Germ Cell and Embryonal - blood
Neoplasms, Germ Cell and Embryonal - pathology
Sarcoma - blood
Sarcoma - pathology
Teratoma - blood
Teratoma - pathology
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Summary:Germ cell tumor(GCT)of the liver is extremely rare. Here,we describe a case of hepatic mixed GCT with significant sarcomatous components and elevated serum α-fetoprotein(AFP)in a 34-year-old man.Histopathologically,the tumor was composed of two GCTs components:yolk sac tumor and immature teratoma.The predominant components of immature teratoma consisted of several types of tissue that represented different germinal layers(endoderm,mesoderm and ectoderm) and showed varying degrees of differentiation with sig...
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v16.i5.652