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Prospective multicenter randomized trial of fast ventricular tachycardia termination by prolonged versus conventional anti-tachyarrhythmia burst pacing in implantable cardioverter-defibrillator patients-Atp DeliVery for pAiNless ICD thErapy (ADVANCE-D) Trial results
Purpose The purpose of the trial was to quantify and compare the efficacy of two different sequences of burst anti-tachycardia pacing (ATP) strategies for the termination of fast ventricular tachycardia. Methods The trial was prospective, multicenter, parallel and randomized, enrolling patients with...
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| Published in: | Journal of interventional cardiac electrophysiology 2010-03, Vol.27 (2), p.127-135 |
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| Main Authors: | , , , , , , , , , , |
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| container_end_page | 135 |
| container_issue | 2 |
| container_start_page | 127 |
| container_title | Journal of interventional cardiac electrophysiology |
| container_volume | 27 |
| creator | Santini, Massimo Lunati, Maurizio Defaye, Pascal Mermi, Johann Proclemer, Alessandro del Castillo-Arroys, Silvia Molon, Giulio Santi, Elisabetta De Santo, Tiziana Navarro, Xavier Kloppe, Axel |
| description | Purpose
The purpose of the trial was to quantify and compare the efficacy of two different sequences of burst anti-tachycardia pacing (ATP) strategies for the termination of fast ventricular tachycardia.
Methods
The trial was prospective, multicenter, parallel and randomized, enrolling patients with an indication for implantable cardioverter-defibrillator implantation.
Results
From February 2004, 925 patients were randomized and followed-up for 12 months. Eight pulses ATP terminated 64% of episodes vs. 70% in the 15-pulse group (
p
= 0.504). Fifteen pulses proved significantly better in patients without a previous history of heart failure (
p
= 0.014) and in patients with LVEF ≥ 40% (
p
= 0.016). No significant differences between groups were observed with regard to syncope/near-syncope occurrence.
Conclusion
In the general population, 15-pulse ATP is as effective and safe as eight-pulse ATP. The efficacy of ATP on fast ventricular arrhythmias confirmed once more the striking importance of careful device programming in order to reduce painful shocks. |
| doi_str_mv | 10.1007/s10840-009-9454-z |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2836470</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1982127321</sourcerecordid><originalsourceid>FETCH-LOGICAL-c534t-ee52a006c1ec2c39e168bac6470eaf51f39588d20621a3f77e35b7d19dfa48c23</originalsourceid><addsrcrecordid>eNp1kktv1DAUhQMC0XbgB7BBFhtgYbCdl7NBGs0MUKkqLErFznIcp-PKiVPbGSnz67mZKeUhsYqlc853c-2TJC8peU8JKT8ESnhGMCEVrrI8w_vHySnNS4Z5XuVP4JzyFPMy_3GSnIVwS8BIWPEsOWGE8LIsyOmjs2_ehUGraHYadaONRuk-ao-87BvXmb1uUPRGWuRa1MoQ0Q50b9RopUdRqu2kpG-MRBDqTC-jcT2qJzR4Z11_A_Gd9mEMSLl-joIMMAkHfEhL77dT3HZAqEcP_EEq098g0yPTDRaMsrYaHYY4QMEY3OjW1N5YK6PzEIgGwAEv44DW2ppr7SfUzsrSXFodAjpfrVHcbrwcJvR2ub5eXq42eP0OXR028zrA4uF58rSVNugX999F8v3T5mr1BV98_Xy-Wl5gladZxFrnTBJSKKoVU2mlacFrqYqsJFq2OW3TKue8YaRgVKZtWeo0r8uGVk0rM65Yukg-HrnDWHe6me_bSysGbzrpJ-GkEX8rvdmKG7cTjKfzFAC8uQd4dzfqEEVngtJwHb12YxBlmqYZY_D4i-T1P85bN3p4gCAY5VVBOcnBRI8mBVUIXrcPv0KJmHsmjj0TUB8x90zsIfPqzx0eEr-KBQZ2NASQoAb-9-T_U38C_2Lnhg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>218961805</pqid></control><display><type>article</type><title>Prospective multicenter randomized trial of fast ventricular tachycardia termination by prolonged versus conventional anti-tachyarrhythmia burst pacing in implantable cardioverter-defibrillator patients-Atp DeliVery for pAiNless ICD thErapy (ADVANCE-D) Trial results</title><source>Springer Nature</source><creator>Santini, Massimo ; Lunati, Maurizio ; Defaye, Pascal ; Mermi, Johann ; Proclemer, Alessandro ; del Castillo-Arroys, Silvia ; Molon, Giulio ; Santi, Elisabetta ; De Santo, Tiziana ; Navarro, Xavier ; Kloppe, Axel</creator><creatorcontrib>Santini, Massimo ; Lunati, Maurizio ; Defaye, Pascal ; Mermi, Johann ; Proclemer, Alessandro ; del Castillo-Arroys, Silvia ; Molon, Giulio ; Santi, Elisabetta ; De Santo, Tiziana ; Navarro, Xavier ; Kloppe, Axel</creatorcontrib><description>Purpose
The purpose of the trial was to quantify and compare the efficacy of two different sequences of burst anti-tachycardia pacing (ATP) strategies for the termination of fast ventricular tachycardia.
Methods
The trial was prospective, multicenter, parallel and randomized, enrolling patients with an indication for implantable cardioverter-defibrillator implantation.
Results
From February 2004, 925 patients were randomized and followed-up for 12 months. Eight pulses ATP terminated 64% of episodes vs. 70% in the 15-pulse group (
p
= 0.504). Fifteen pulses proved significantly better in patients without a previous history of heart failure (
p
= 0.014) and in patients with LVEF ≥ 40% (
p
= 0.016). No significant differences between groups were observed with regard to syncope/near-syncope occurrence.
Conclusion
In the general population, 15-pulse ATP is as effective and safe as eight-pulse ATP. The efficacy of ATP on fast ventricular arrhythmias confirmed once more the striking importance of careful device programming in order to reduce painful shocks.</description><identifier>ISSN: 1383-875X</identifier><identifier>EISSN: 1572-8595</identifier><identifier>DOI: 10.1007/s10840-009-9454-z</identifier><identifier>PMID: 20087760</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Cardiac Pacing, Artificial - mortality ; Cardiology ; Electric Countershock - mortality ; Europe ; Female ; Humans ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Prevalence ; Prospective Studies ; Risk Assessment - methods ; Risk Factors ; Survival Analysis ; Survival Rate ; Tachycardia, Ventricular - mortality ; Tachycardia, Ventricular - prevention & control ; Treatment Outcome</subject><ispartof>Journal of interventional cardiac electrophysiology, 2010-03, Vol.27 (2), p.127-135</ispartof><rights>The Author(s) 2010</rights><rights>Springer Science+Business Media, LLC 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c534t-ee52a006c1ec2c39e168bac6470eaf51f39588d20621a3f77e35b7d19dfa48c23</citedby><cites>FETCH-LOGICAL-c534t-ee52a006c1ec2c39e168bac6470eaf51f39588d20621a3f77e35b7d19dfa48c23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20087760$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Santini, Massimo</creatorcontrib><creatorcontrib>Lunati, Maurizio</creatorcontrib><creatorcontrib>Defaye, Pascal</creatorcontrib><creatorcontrib>Mermi, Johann</creatorcontrib><creatorcontrib>Proclemer, Alessandro</creatorcontrib><creatorcontrib>del Castillo-Arroys, Silvia</creatorcontrib><creatorcontrib>Molon, Giulio</creatorcontrib><creatorcontrib>Santi, Elisabetta</creatorcontrib><creatorcontrib>De Santo, Tiziana</creatorcontrib><creatorcontrib>Navarro, Xavier</creatorcontrib><creatorcontrib>Kloppe, Axel</creatorcontrib><title>Prospective multicenter randomized trial of fast ventricular tachycardia termination by prolonged versus conventional anti-tachyarrhythmia burst pacing in implantable cardioverter-defibrillator patients-Atp DeliVery for pAiNless ICD thErapy (ADVANCE-D) Trial results</title><title>Journal of interventional cardiac electrophysiology</title><addtitle>J Interv Card Electrophysiol</addtitle><addtitle>J Interv Card Electrophysiol</addtitle><description>Purpose
The purpose of the trial was to quantify and compare the efficacy of two different sequences of burst anti-tachycardia pacing (ATP) strategies for the termination of fast ventricular tachycardia.
Methods
The trial was prospective, multicenter, parallel and randomized, enrolling patients with an indication for implantable cardioverter-defibrillator implantation.
Results
From February 2004, 925 patients were randomized and followed-up for 12 months. Eight pulses ATP terminated 64% of episodes vs. 70% in the 15-pulse group (
p
= 0.504). Fifteen pulses proved significantly better in patients without a previous history of heart failure (
p
= 0.014) and in patients with LVEF ≥ 40% (
p
= 0.016). No significant differences between groups were observed with regard to syncope/near-syncope occurrence.
Conclusion
In the general population, 15-pulse ATP is as effective and safe as eight-pulse ATP. The efficacy of ATP on fast ventricular arrhythmias confirmed once more the striking importance of careful device programming in order to reduce painful shocks.</description><subject>Cardiac Pacing, Artificial - mortality</subject><subject>Cardiology</subject><subject>Electric Countershock - mortality</subject><subject>Europe</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Prevalence</subject><subject>Prospective Studies</subject><subject>Risk Assessment - methods</subject><subject>Risk Factors</subject><subject>Survival Analysis</subject><subject>Survival Rate</subject><subject>Tachycardia, Ventricular - mortality</subject><subject>Tachycardia, Ventricular - prevention & control</subject><subject>Treatment Outcome</subject><issn>1383-875X</issn><issn>1572-8595</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNp1kktv1DAUhQMC0XbgB7BBFhtgYbCdl7NBGs0MUKkqLErFznIcp-PKiVPbGSnz67mZKeUhsYqlc853c-2TJC8peU8JKT8ESnhGMCEVrrI8w_vHySnNS4Z5XuVP4JzyFPMy_3GSnIVwS8BIWPEsOWGE8LIsyOmjs2_ehUGraHYadaONRuk-ao-87BvXmb1uUPRGWuRa1MoQ0Q50b9RopUdRqu2kpG-MRBDqTC-jcT2qJzR4Z11_A_Gd9mEMSLl-joIMMAkHfEhL77dT3HZAqEcP_EEq098g0yPTDRaMsrYaHYY4QMEY3OjW1N5YK6PzEIgGwAEv44DW2ppr7SfUzsrSXFodAjpfrVHcbrwcJvR2ub5eXq42eP0OXR028zrA4uF58rSVNugX999F8v3T5mr1BV98_Xy-Wl5gladZxFrnTBJSKKoVU2mlacFrqYqsJFq2OW3TKue8YaRgVKZtWeo0r8uGVk0rM65Yukg-HrnDWHe6me_bSysGbzrpJ-GkEX8rvdmKG7cTjKfzFAC8uQd4dzfqEEVngtJwHb12YxBlmqYZY_D4i-T1P85bN3p4gCAY5VVBOcnBRI8mBVUIXrcPv0KJmHsmjj0TUB8x90zsIfPqzx0eEr-KBQZ2NASQoAb-9-T_U38C_2Lnhg</recordid><startdate>20100301</startdate><enddate>20100301</enddate><creator>Santini, Massimo</creator><creator>Lunati, Maurizio</creator><creator>Defaye, Pascal</creator><creator>Mermi, Johann</creator><creator>Proclemer, Alessandro</creator><creator>del Castillo-Arroys, Silvia</creator><creator>Molon, Giulio</creator><creator>Santi, Elisabetta</creator><creator>De Santo, Tiziana</creator><creator>Navarro, Xavier</creator><creator>Kloppe, Axel</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20100301</creationdate><title>Prospective multicenter randomized trial of fast ventricular tachycardia termination by prolonged versus conventional anti-tachyarrhythmia burst pacing in implantable cardioverter-defibrillator patients-Atp DeliVery for pAiNless ICD thErapy (ADVANCE-D) Trial results</title><author>Santini, Massimo ; Lunati, Maurizio ; Defaye, Pascal ; Mermi, Johann ; Proclemer, Alessandro ; del Castillo-Arroys, Silvia ; Molon, Giulio ; Santi, Elisabetta ; De Santo, Tiziana ; Navarro, Xavier ; Kloppe, Axel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c534t-ee52a006c1ec2c39e168bac6470eaf51f39588d20621a3f77e35b7d19dfa48c23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Cardiac Pacing, Artificial - mortality</topic><topic>Cardiology</topic><topic>Electric Countershock - mortality</topic><topic>Europe</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Prevalence</topic><topic>Prospective Studies</topic><topic>Risk Assessment - methods</topic><topic>Risk Factors</topic><topic>Survival Analysis</topic><topic>Survival Rate</topic><topic>Tachycardia, Ventricular - mortality</topic><topic>Tachycardia, Ventricular - prevention & control</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Santini, Massimo</creatorcontrib><creatorcontrib>Lunati, Maurizio</creatorcontrib><creatorcontrib>Defaye, Pascal</creatorcontrib><creatorcontrib>Mermi, Johann</creatorcontrib><creatorcontrib>Proclemer, Alessandro</creatorcontrib><creatorcontrib>del Castillo-Arroys, Silvia</creatorcontrib><creatorcontrib>Molon, Giulio</creatorcontrib><creatorcontrib>Santi, Elisabetta</creatorcontrib><creatorcontrib>De Santo, Tiziana</creatorcontrib><creatorcontrib>Navarro, Xavier</creatorcontrib><creatorcontrib>Kloppe, Axel</creatorcontrib><collection>SpringerOpen (Open Access)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of interventional cardiac electrophysiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Santini, Massimo</au><au>Lunati, Maurizio</au><au>Defaye, Pascal</au><au>Mermi, Johann</au><au>Proclemer, Alessandro</au><au>del Castillo-Arroys, Silvia</au><au>Molon, Giulio</au><au>Santi, Elisabetta</au><au>De Santo, Tiziana</au><au>Navarro, Xavier</au><au>Kloppe, Axel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prospective multicenter randomized trial of fast ventricular tachycardia termination by prolonged versus conventional anti-tachyarrhythmia burst pacing in implantable cardioverter-defibrillator patients-Atp DeliVery for pAiNless ICD thErapy (ADVANCE-D) Trial results</atitle><jtitle>Journal of interventional cardiac electrophysiology</jtitle><stitle>J Interv Card Electrophysiol</stitle><addtitle>J Interv Card Electrophysiol</addtitle><date>2010-03-01</date><risdate>2010</risdate><volume>27</volume><issue>2</issue><spage>127</spage><epage>135</epage><pages>127-135</pages><issn>1383-875X</issn><eissn>1572-8595</eissn><abstract>Purpose
The purpose of the trial was to quantify and compare the efficacy of two different sequences of burst anti-tachycardia pacing (ATP) strategies for the termination of fast ventricular tachycardia.
Methods
The trial was prospective, multicenter, parallel and randomized, enrolling patients with an indication for implantable cardioverter-defibrillator implantation.
Results
From February 2004, 925 patients were randomized and followed-up for 12 months. Eight pulses ATP terminated 64% of episodes vs. 70% in the 15-pulse group (
p
= 0.504). Fifteen pulses proved significantly better in patients without a previous history of heart failure (
p
= 0.014) and in patients with LVEF ≥ 40% (
p
= 0.016). No significant differences between groups were observed with regard to syncope/near-syncope occurrence.
Conclusion
In the general population, 15-pulse ATP is as effective and safe as eight-pulse ATP. The efficacy of ATP on fast ventricular arrhythmias confirmed once more the striking importance of careful device programming in order to reduce painful shocks.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>20087760</pmid><doi>10.1007/s10840-009-9454-z</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1383-875X |
| ispartof | Journal of interventional cardiac electrophysiology, 2010-03, Vol.27 (2), p.127-135 |
| issn | 1383-875X 1572-8595 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2836470 |
| source | Springer Nature |
| subjects | Cardiac Pacing, Artificial - mortality Cardiology Electric Countershock - mortality Europe Female Humans Male Medicine Medicine & Public Health Middle Aged Prevalence Prospective Studies Risk Assessment - methods Risk Factors Survival Analysis Survival Rate Tachycardia, Ventricular - mortality Tachycardia, Ventricular - prevention & control Treatment Outcome |
| title | Prospective multicenter randomized trial of fast ventricular tachycardia termination by prolonged versus conventional anti-tachyarrhythmia burst pacing in implantable cardioverter-defibrillator patients-Atp DeliVery for pAiNless ICD thErapy (ADVANCE-D) Trial results |
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