Comparison of Drug Permeabilities and BCS Classification: Three Lipid-Component PAMPA System Method versus Caco-2 Monolayers

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Bibliographic Details
Published in:The AAPS journal 2010-06, Vol.12 (2), p.238-241
Main Authors: Teksin, Zeynep S., Seo, Paul R., Polli, James E.
Format: Article
Language:English
Subjects:
Adrenergic beta-Antagonists - metabolism
Animals
Biochemistry
Biomedical and Life Sciences
Biomedicine
Biotechnology
Brief/Technical Note
Caco-2 Cells
Cell Line
Cell Membrane Permeability - drug effects
Dogs
Humans
Membranes, Artificial
Metoprolol - metabolism
Pharmaceutical Preparations - classification
Pharmaceutical Preparations - metabolism
Pharmacology/Toxicology
Pharmacy
Predictive Value of Tests
Reference Standards
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ISSN:1550-7416
1550-7416
DOI:10.1208/s12248-010-9176-2