The role of the right inferior frontal gyrus: inhibition and attentional control

There is growing interest regarding the role of the right inferior frontal gyrus (RIFG) during a particular form of executive control referred to as response inhibition. However, tasks used to examine neural activity at the point of response inhibition have rarely controlled for the potentially conf...

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Published in:NeuroImage (Orlando, Fla.) Fla.), 2010-04, Vol.50 (3), p.1313-1319
Main Authors: Hampshire, Adam, Chamberlain, Samuel R., Monti, Martin M., Duncan, John, Owen, Adrian M.
Format: Article
Language:English
Subjects:
Attention - physiology
Attention deficit hyperactivity disorder
Brain - physiology
Cues
Executive Function - physiology
Frontal Lobe - physiology
Functional Laterality
Humans
Hyperactivity
Hypotheses
Magnetic Resonance Imaging
Motor Activity - physiology
Neuropsychological Tests
Psychomotor Performance - physiology
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creator Hampshire, Adam
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description There is growing interest regarding the role of the right inferior frontal gyrus (RIFG) during a particular form of executive control referred to as response inhibition. However, tasks used to examine neural activity at the point of response inhibition have rarely controlled for the potentially confounding effects of attentional demand. In particular, it is unclear whether the RIFG is specifically involved in inhibitory control, or is involved more generally in the detection of salient or task relevant cues. The current fMRI study sought to clarify the role of the RIFG in executive control by holding the stimulus conditions of one of the most popular response inhibition tasks–the Stop Signal Task–constant, whilst varying the response that was required on reception of the stop signal cue. Our results reveal that the RIFG is recruited when important cues are detected, regardless of whether that detection is followed by the inhibition of a motor response, the generation of a motor response, or no external response at all.
doi_str_mv 10.1016/j.neuroimage.2009.12.109
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subjects Attention - physiology
Attention deficit hyperactivity disorder
Brain - physiology
Cues
Executive Function - physiology
Frontal Lobe - physiology
Functional Laterality
Humans
Hyperactivity
Hypotheses
Magnetic Resonance Imaging
Motor Activity - physiology
Neuropsychological Tests
Psychomotor Performance - physiology
title The role of the right inferior frontal gyrus: inhibition and attentional control
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