Clinicopathological significance and prognostic value of LRP16 expression in colorectal carcinoma

AIM: To explore the expression of leukemia related protein 16 (LRP16) in colorectal carcinoma, and analyze its correlation with clinicopathologic features and prognosis. METHODS: Immunohistochemistry for LRP16 was performed in 201 cases of colorectal carcinoma and 60 cases of distal normal mucosa. M...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2010-04, Vol.16 (13), p.1644-1648
Main Authors: Xi, Hong Qing, Zhao, Po, Han, Wei Dong
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Brief
Carcinoma - diagnosis
Carcinoma - metabolism
Colorectal Neoplasms - diagnosis
Colorectal Neoplasms - metabolism
Female
Gene Expression Regulation, Neoplastic
Humans
Immunohistochemistry - methods
Intestinal Mucosa - pathology
Male
Middle Aged
Neoplasm Proteins - biosynthesis
Neoplasm Proteins - physiology
Prognosis
Proportional Hazards Models
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Summary:AIM: To explore the expression of leukemia related protein 16 (LRP16) in colorectal carcinoma, and analyze its correlation with clinicopathologic features and prognosis. METHODS: Immunohistochemistry for LRP16 was performed in 201 cases of colorectal carcinoma and 60 cases of distal normal mucosa. Medical records were reviewed and clinicopathological analysis was performed. RESULTS: LRP16 expression was detected in 117 of 201 cases of the colorectal carcinoma and in 21 cases of 60 distal normal mucosa. The ...
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v16.i13.1644