Community attitudes towards emergency research and exception from informed consent

• Published in: Resuscitation 2009-12, Vol.80 (12), p.1382-1387
• Main Authors: Biros, Michelle H, Sargent, Corey, Miller, Kathleen
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Biomedical Research; Clinical Trials as Topic; Community consultation; Educational Status; Emergency; Emergency and intensive care: techniques, logistics; Emergency Medicine; Emergency research emergency exception form informed consent; Female; Humans; Income; Informed Consent; Intensive care medicine; Intensive care unit. Emergency transport systems. Emergency, hospital ward; Linear Models; Logistic Models; Male; Medical sciences; Middle Aged; Public Opinion; Surveys and Questionnaires
• ISSN: 0300-9572; 1873-1570
• DOI: 10.1016/j.resuscitation.2009.08.019

Abstract Objective To determine public attitudes towards emergency research, exception from informed consent (EFIC) and a specific proposed clinical trial using EFIC. Methods As part of a planned community consultation activity, a survey was conducted at a popular public venue. Participants answered demographic questions and then were asked their opinions on specifically described consent circumstances in emergency research, including the proposed EFIC trial. Multiple logistic and linear regression were used to determine respondent characteristics associated with specific attitudes. Results 1901 surveys were completed. The majority of respondents supported emergency research (88%) and the concept of surrogate consent by a legally authorized representative (78%). The concept of EFIC was less well supported (35%) but the application of EFIC was more accepted, especially when EFIC was applied to the respondent themselves (51%). The community believed the proposed EFIC study was acceptable (82%); a minority had concerns but most were related to patient safety and not to EFIC. Respondents with less education and lower incomes were less likely to express opinions about the consent and research concepts described. Conclusions Emergency research and the proposed EFIC trial is supported in this community. The concept of EFIC is less well supported but is more acceptable when a specific trial is described or when respondents consider EFIC for themselves. Specific respondent characteristics are associated with attitudes about research; this can assist in development of meaningful community consultation activities.