Postprandial insulin and triglycerides after different breakfast meal challenges: use of finger stick capillary dried blood spots to study postprandial dysmetabolism

High levels of insulin and lipids following a meal are recognized risk factors for atherosclerosis. Monitoring such risk factors in the general population is hampered by the inconvenience of venipuncture blood collection, particularly for both premeal and postmeal analyses. This study examined insul...

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Bibliographic Details
Published in:Journal of diabetes science and technology 2010-03, Vol.4 (2), p.236-243
Main Authors: Kapur, Sonia, Groves, Margaret N, Zava, David T, Kapur, Sanjay
Format: Article
Language:English
Subjects:
Blood Glucose - metabolism
Dairy Products
Eggs
Energy Intake
Fasting
Humans
Insulin - blood
Meat
Metabolic Syndrome - blood
Postprandial Period
Reference Values
Risk Assessment
Symposium
Time Factors
Triglycerides - blood
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Summary:High levels of insulin and lipids following a meal are recognized risk factors for atherosclerosis. Monitoring such risk factors in the general population is hampered by the inconvenience of venipuncture blood collection, particularly for both premeal and postmeal analyses. This study examined insulin and triglyceride levels in dried blood spots (DBSs) collected after different breakfast meal challenges to assess the potential of this method for risk assessment. Glucose levels were measured using a glucose meter, and insulin and triglycerides were determined in DBS samples collected from 19 healthy volunteers before and at four time points up to 2.5 h after consuming each of five typical breakfast meals varying in nutritional composition. At 2 h, glucose was within normal postprandial values (
ISSN:1932-2968
1932-3107
DOI:10.1177/193229681000400202