Management of chronic hepatitis C in French departments of internal medicine and infectious diseases

This prospective, multicentre study was conducted during 2–30 April 2001 in the internal medicine/infectious diseases services in France and included data from 1858 hepatitis C virus (HCV)-infected patients, half of whom were HIV co-infected. The aims were to outline the type of pre-therapeutic eval...

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Bibliographic Details
Published in:Epidemiology and infection 2005-04, Vol.133 (2), p.305-314
Main Authors: CACOUB, P., GODEREL, I., MORLAT, P., SENE, D., MYERS, R. P., ALRIC, L., LOUSTAUD-RATTI, V., MELIN, P., LIMAL, N., OUZAN, D., PERRONNE, C., CARRAT, F.
Format: Article
Language:English
Subjects:
Adult
Antigens
Antiviral Agents - therapeutic use
Antivirals
Biochemistry
Biological and medical sciences
Biopsies
Biopsy
Chronic hepatitis
Cirrhosis
Departments
Drug use
Epidemiology
Female
France
Fundamental and applied biological sciences. Psychology
Gastroenterology
Genotype
Genotype & phenotype
Hepacivirus
Hepatitis B
Hepatitis B, Chronic - complications
Hepatitis B, Chronic - diagnosis
Hepatitis B, Chronic - drug therapy
Hepatitis C
Hepatology
HIV
HIV Infections - drug therapy
Hospitals, University - statistics & numerical data
Human viral diseases
Humans
Infections
Infectious diseases
Interferons
Internal medicine
Internal Medicine - statistics & numerical data
Liver
Liver - pathology
Liver cancer
Male
Medical sciences
Medicine
Microbiology
Middle Aged
Patients
Physicians
Prospective Studies
RNA
RNA, Viral - analysis
Substance Abuse, Intravenous
Viral diseases
Viral hepatitis
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Summary:This prospective, multicentre study was conducted during 2–30 April 2001 in the internal medicine/infectious diseases services in France and included data from 1858 hepatitis C virus (HCV)-infected patients, half of whom were HIV co-infected. The aims were to outline the type of pre-therapeutic evaluation of HCV infection performed (HCV RNA, genotype, liver biopsy); determine the proportion and characteristics of patients receiving antiviral treatment; and determine if any changes in these parameters had occurred between 1995 and 2001. Patients whom had a complete pre-therapeutic evaluation (39%, 709/1834) and received antiviral treatment (38%, 690/1830) were more likely to have abnormal liver biochemistry, cirrhosis and cryoglobulinaemia (P
ISSN:0950-2688
1469-4409
DOI:10.1017/S0950268804003486