Intra-familial spread of hepatitis B virus infection in eastern Turkey

Hepatitis B virus (HBV) infection is a worldwide health problem. The aim of the present study was not only to determine the prevalence of HBsAg in children of HBV-infected parents but also to identify all HBSAg-positive family members to protect as many children, in the present and future, as possib...

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Bibliographic Details
Published in:Epidemiology and infection 2007-11, Vol.135 (8), p.1338-1343
Main Authors: UCMAK, H., FARUK KOKOGLU, O., CELIK, M., ERGUN, U. G. O.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age groups
Aged
Biological and medical sciences
Child
Children
Disease Transmission, Infectious
Epidemiology
Family Health
Family members
Fathers
Female
Hepatitis antigens
Hepatitis B
Hepatitis B - epidemiology
Hepatitis B - transmission
Hepatitis B Surface Antigens - blood
Hepatitis B virus
Human viral diseases
Humans
Immunoenzyme Techniques
Infections
Infectious diseases
Male
Medical sciences
Middle Aged
Mothers
Prevalence
Turkey - epidemiology
Viral diseases
Viral hepatitis
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Summary:Hepatitis B virus (HBV) infection is a worldwide health problem. The aim of the present study was not only to determine the prevalence of HBsAg in children of HBV-infected parents but also to identify all HBSAg-positive family members to protect as many children, in the present and future, as possible. The study was carried out with the participation of 2113 family members (1205 children, 453 mothers, and 455 fathers) at Sivas SSK Hospital, Turkey. They were screened for HBV markers using standard enzyme immunoassay between September 2001 and March 2005. The prevalence of any HBV markers and HBsAg among family members of index cases was 50·5% and 30·5% respectively. HBsAg carrier rate was higher among fathers (61%) than mothers (47%), (P
ISSN:0950-2688
1469-4409
DOI:10.1017/S0950268807008011