Functional Consequences of HIV-Associated Neuropsychological Impairment

This review focuses on the “real world” implications of infection with HIV/AIDS from a neuropsychological perspective. Relevant literature is reviewed which examines the relationships between HIV-associated neuropsychological impairment and employment, driving, medication adherence, mood, fatigue, a...

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Bibliographic Details
Published in:Neuropsychology review 2009-06, Vol.19 (2), p.186-203
Main Authors: Gorman, Ashley A., Foley, Jessica M., Ettenhofer, Mark L., Hinkin, Charles H., van Gorp, Wilfred G.
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Acquired Immunodeficiency Syndrome - complications
Acquired Immunodeficiency Syndrome - psychology
AIDS
AIDS Dementia Complex - psychology
Anti-Retroviral Agents - therapeutic use
Antiretroviral Therapy, Highly Active - methods
Biomedical and Life Sciences
Biomedicine
Central Nervous System Diseases - etiology
Central Nervous System Diseases - psychology
Central Nervous System Diseases - virology
Chronic illnesses
Cognition Disorders - etiology
Cognition Disorders - psychology
Cognition Disorders - virology
Cost of Illness
Employment
HIV
HIV Infections - complications
HIV Infections - psychology
Human immunodeficiency virus
Humans
Neurology
Neuropsychological Tests
Neuropsychology
Neurosciences
Quality of Life
Review
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Summary:This review focuses on the “real world” implications of infection with HIV/AIDS from a neuropsychological perspective. Relevant literature is reviewed which examines the relationships between HIV-associated neuropsychological impairment and employment, driving, medication adherence, mood, fatigue, and interpersonal functioning. Specifically, the relative contributions of medical, cognitive, psychosocial, and psychiatric issues on whether someone with HIV/AIDS will be able to return to work, adhere to a complicated medication regimen, or safely drive a vehicle will be discussed. Methodological issues that arise in the context of measuring medication adherence or driving capacity are also explored. Finally, the impact of HIV/AIDS on mood state, fatigue, and interpersonal relationships are addressed, with particular emphasis on how these variables interact with cognition and independent functioning. The purpose of this review is to integrate neuropsychological findings with their real world correlates of functional behavior in the HIV/AIDS population.
ISSN:1040-7308
1573-6660
DOI:10.1007/s11065-009-9095-0