Synthesis of substituted N-[4(5-methyl/phenyl-1,3,4-oxadiazol-2-yl)-3,6-dihydropyridin-1(2H)-yl]benzamide/benzene sulfonamides as anti-inflammatory and anti-cancer agents

Fourteen novel substituted N‐[4(5‐methyl/phenyl‐1,3,4‐oxadiazol‐2‐yl)‐3,6‐dihydropyridin‐1(2H)‐yl] benzamide/benzene sulfonamides (11a, 11b, 11c, 11d, 11e, 11f, 11g, 11h, 11i, 11j, 11k, 11l, 11m, 11n) were synthesized in fair to good yields via sodium borohydride reduction of the corresponding subst...

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Published in:Journal of heterocyclic chemistry 2009-03, Vol.46 (2), p.309-316
Main Authors: Gangapuram, Madhavi, Redda, Kinfe K.
Format: Article
Language:English
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Summary:Fourteen novel substituted N‐[4(5‐methyl/phenyl‐1,3,4‐oxadiazol‐2‐yl)‐3,6‐dihydropyridin‐1(2H)‐yl] benzamide/benzene sulfonamides (11a, 11b, 11c, 11d, 11e, 11f, 11g, 11h, 11i, 11j, 11k, 11l, 11m, 11n) were synthesized in fair to good yields via sodium borohydride reduction of the corresponding substituted N‐(benzoylimino)‐4‐(5‐methyl/5‐phenyl‐1,3,4‐oxadiazol‐2yl) pyridinium ylide 10a, 10b, 10c, 10d, 10e, 10f, 10g, 10h, 10i, 10j, 10k, 10m, 10n in absolute ethanol. J. Heterocyclic Chem., (2009)
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.62