Microarray-Based Gene Expression Analysis of Hepatocellular Carcinoma

Microarray studies have successfully shed light on various aspects of the molecular mechanisms behind the development of hepatocellular carcinoma (HCC), such as the identification of novel molecular subgroups and the genetic profiles associated with metastasis and venous invasion. These experiments,...

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Published in:Current genomics 2010-06, Vol.11 (4), p.261-268
Main Authors: Maass, Thorsten, Sfakianakis, Ioannis, Staib, Frank, Krupp, Markus, Galle, Peter R, Teufel, Andreas
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Language:English
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container_title Current genomics
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creator Maass, Thorsten
Sfakianakis, Ioannis
Staib, Frank
Krupp, Markus
Galle, Peter R
Teufel, Andreas
description Microarray studies have successfully shed light on various aspects of the molecular mechanisms behind the development of hepatocellular carcinoma (HCC), such as the identification of novel molecular subgroups and the genetic profiles associated with metastasis and venous invasion. These experiments, mainly comprising genome wide profiling, potentially represent the basis of novel targeted therapeutic strategies in HCC. In response, we summarize the multiple reported expression profiles in HCC associated with HCC development, novel subgroups, venous invasion and metastasis.
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title Microarray-Based Gene Expression Analysis of Hepatocellular Carcinoma
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