A Clinical Isolate of Candida albicans with Mutations in ERG11 (Encoding Sterol 14α-Demethylase) and ERG5 (Encoding C22 Desaturase) Is Cross Resistant to Azoles and Amphotericin B

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Published in:Antimicrobial Agents and Chemotherapy 2010-09, Vol.54 (9), p.3578-3583
Main Authors: Martel, Claire M, Parker, Josie E, Bader, Oliver, Weig, Michael, Gross, Uwe, Warrilow, Andrew G S, Kelly, Diane E, Kelly, Steven L
Format: Article
Language:English
Subjects:
Amphotericin B
Amphotericin B - pharmacology
Antifungal Agents
Antifungal Agents - pharmacology
Azoles
Azoles - pharmacology
Candida albicans
Candida albicans - drug effects
Candida albicans - genetics
Drug Resistance, Fungal
Drug Resistance, Fungal - genetics
Fungal Proteins
Fungal Proteins - genetics
Mechanisms of Resistance
Microbial Sensitivity Tests
Mutation
Polymerase Chain Reaction
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.00303-10