Oncogenic osteomalacia: Problems in diagnosis and long-term management

Oncogenic osteomalacia is a rare association between mesenchymal tumors and hypophosphatemic rickets. It is more of a biochemical entity than a clinical one. The pathophysiology of the tumor is not clear. However, it has been seen that the clinical and biochemical parameters become normal if the les...

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Bibliographic Details
Published in:Indian journal of orthopaedics 2010-10, Vol.44 (4), p.453-457
Main Authors: Dhammi, Ish K., Jain, Anil K., Pal, Ajay, Mishra, Puneet, Jain, Saurabh
Format: Article
Language:English
Subjects:
Bones
Case Report
Conservative Orthopedics
Diagnosis
Medicine & Public Health
Orthopedics
Stem cells
Surgical Orthopedics
Tumors
Vitamin D
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Summary:Oncogenic osteomalacia is a rare association between mesenchymal tumors and hypophosphatemic rickets. It is more of a biochemical entity than a clinical one. The pathophysiology of the tumor is not clear. However, it has been seen that the clinical and biochemical parameters become normal if the lesion responsible for producing the osteomalacia is excised. For a clinical diagnosis a high index of suspicion is necessary. We present three such cases where in one the oncogenic osteomalacia reversed while in rest it did not. We present this case report to sensitize about the entity.
ISSN:0019-5413
1998-3727
DOI:10.4103/0019-5413.69320