Evaluation of the Capilia TB Assay for Culture Confirmation of Mycobacterium tuberculosis Infections in Zambia and South Africa

The performance and cost of the Capilia TB assay were evaluated for use in a resource-limited setting. The sensitivity and specificity were 99.6% and 99.5%, respectively. The incremental costs of the Capilia test were estimated to be $1.46 and $1.84 when the test was added to liquid and solid cultur...

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Bibliographic Details
Published in:Journal of Clinical Microbiology 2010-10, Vol.48 (10), p.3773-3775
Main Authors: Muyoyeta, Monde, de Haas, Petra E.W, Mueller, Dirk H, van Helden, Paul D, Mwenge, Lawrence, Schaap, Ab, Kruger, Clarissa, Gey van Pittius, Nicolaas C, Lawrence, Katherine, Beyers, Nulda, Godfrey-Faussett, Peter, Ayles, Helen
Format: Article
Language:English
Subjects:
Bacteriological Techniques - economics
Bacteriological Techniques - methods
Bacteriology
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Humans
Microbiology
Miscellaneous
Mycobacteriology and Aerobic Actinomycetes
Mycobacterium tuberculosis
Mycobacterium tuberculosis - isolation & purification
Sensitivity and Specificity
South Africa
Time Factors
Tuberculosis - diagnosis
Zambia
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Summary:The performance and cost of the Capilia TB assay were evaluated for use in a resource-limited setting. The sensitivity and specificity were 99.6% and 99.5%, respectively. The incremental costs of the Capilia test were estimated to be $1.46 and $1.84 when the test was added to liquid and solid culture processes, respectively. These findings suggest that the Capilia TB assay represents a rapid, simple, and inexpensive Mycobacterium tuberculosis identification test that can be used in resource-limited settings.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.01688-09