Flucytosine for treatment of Candida albicans in H1N1-positive patient

A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which was complicated by empyema thoracis due to Candida albicans. Hematogenous spread was suspected as simultaneous culture of ascitic fluid identified Candida specie...

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Bibliographic Details
Published in:Indian journal of pharmacology 2010-09, Vol.42 (5), p.318-319
Main Authors: Samra, Tanvir, Yadav, Amlendu, Banerjee, Neerja, Pawar, Mridula, Deepak, Desh
Format: Article
Language:English
Subjects:
Candida albicans
Care and treatment
Drug Watch
Flucytosine
Properties
Swine influenza
Viral pneumonia
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Summary:A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which was complicated by empyema thoracis due to Candida albicans. Hematogenous spread was suspected as simultaneous culture of ascitic fluid identified Candida species sensitive to flucytosine but resistant to amphotericin B and azole group of antifungals. Monotherapy with flucytosine led to clinical and radiological improvement.
ISSN:0253-7613
1998-3751
DOI:10.4103/0253-7613.70398