Primary Leiomyosarcoma of the Kidney

Primary leiomyosarcoma of the kidney is a rare tumor with an aggressive behaviour. A 55-year-old woman presented with a left sided abdominal mass in our outpatient department. Radiologic investigations revealed the mass to be renal in origin with colonic adhesions for which radical nephrectomy and h...

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Bibliographic Details
Published in:Pathology Research International 2010-02, Vol.2010 (2010), p.115-118
Main Authors: Venkatesh, Kusuma, Lamba Saini, Monika, Niveditha, S. R., Krishnagiri, Chaithra, Babu, Sudarshan
Format: Article
Language:English
Subjects:
Care and treatment
Case Report
Case studies
Diagnosis
Kidney cancer
Leiomyosarcoma
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Summary:Primary leiomyosarcoma of the kidney is a rare tumor with an aggressive behaviour. A 55-year-old woman presented with a left sided abdominal mass in our outpatient department. Radiologic investigations revealed the mass to be renal in origin with colonic adhesions for which radical nephrectomy and hemicolectomy were done. The tumor completely appeared to replace the left kidney and had a whorled character focally on cut section. Microscopically, spindle cells having malignant features with cigar shaped nuclei were seen. The smooth muscle origin of the cells was confirmed by immunohistochemical positivity for smooth muscle actin. Sarcomatoid variant of the renal cell carcinoma was ruled out as the tumor was negative for cytokeratin. Tumors with spindle cell morphology in the kidney should not always be taken for a sarcomatoid variant of renal cell carcinoma and should be investigated thoroughly.
ISSN:2090-8091
2042-003X
2042-003X
DOI:10.4061/2010/652398