MRI-based prostate brachytherapy seed localization

A magnetic resonance imaging (MRI) pulse sequence and a corresponding image processing algorithm to localize prostate brachytherapy seeds during or after therapy are presented. Inversion-Recovery with ON-resonant water suppression (IRON) is an MRI methodology that generates positive contrast in regi...

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Bibliographic Details
Published in:2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro 2010-04, Vol.2010, p.1397-1400
Main Authors: Kuo, Nathanael, Junghoon Lee, Tempany, Clare, Stuber, Matthias, Prince, Jerry
Format: Article
Language:English
Subjects:
blob detection
Brachytherapy
Image processing
Imaging phantoms
Iron
Magnetic fields
Magnetic materials
Magnetic resonance imaging
Magnetic susceptibility
Medical treatment
Optical imaging
positive contrast
prostate brachytherapy
seed localization
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Summary:A magnetic resonance imaging (MRI) pulse sequence and a corresponding image processing algorithm to localize prostate brachytherapy seeds during or after therapy are presented. Inversion-Recovery with ON-resonant water suppression (IRON) is an MRI methodology that generates positive contrast in regions of magnetic field susceptibility, as created by prostate brachytherapy seeds. Phantoms comprising of several materials found in brachytherapy seeds were created to assess the usability of the IRON pulse sequence for imaging seeds. Resulting images show that seed materials are clearly visible with high contrast using IRON, agreeing with theoretical predictions. A seed localization algorithm to process IRON images demonstrates the potential of this imaging technique for seed localization and dosimetry.
ISSN:1945-7928
1945-8452
DOI:10.1109/ISBI.2010.5490259