Peritoneal carcinomatosis of colorectal origin

Peritoneal carcinomatosis is,after liver metastases,the second most frequent cause of death in colorectal cancer patients and at the present time,is commonly inserted and treated as a stage Ⅳ tumour.Because there is no published data that outlines the impact of new therapeutic regimens on survival o...

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Bibliographic Details
Published in:World journal of gastrointestinal oncology 2010-02, Vol.2 (2), p.98-101
Main Authors: Macrì, Antonio, Saladino, Edoardo, Bartolo, Vincenzo, Adamo, Vincenzo, Altavilla, Giuseppe, Mondello, Epifanio, Condemi, Giovanni, Sinardi, Angelo, Famulari, Ciro
Format: Article
Language:English
Subjects:
cancer
carcinomatosis
chemotherapy
Colorectal
Cytoreductive
Hyperthermic
intraperitoneal
Peritoneal
surgery
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Summary:Peritoneal carcinomatosis is,after liver metastases,the second most frequent cause of death in colorectal cancer patients and at the present time,is commonly inserted and treated as a stage Ⅳ tumour.Because there is no published data that outlines the impact of new therapeutic regimens on survival of patients with peritoneal surface diffusion,the story of carcinomatosis can be rewritten in light of a new aggressive approach based on the combination of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.Also if these treatment perhaps allow to obtain better results than standard therapies,we suggest,that a large prospective randomised control trial is needed to compare long-term and progression-free survival under the best available systemic therapy with or without cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
ISSN:1948-5204
1948-5204
DOI:10.4251/wjgo.v2.i2.98