Differences between main-duct and branch-duct intraductal papillary mucinous neoplasms of the pancreas

In the last decade,intraductal papillary mucinous neoplasms(IPMNs) have become commonly diagnosed.From a morphological standpoint,they are classified in main-duct IPMNs(MD-IPMNs) and branch-duct IPMNs(BD-IPMNs),depending on the type of involvement of the pancreatic ductal system by the neoplasm.Desp...

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Bibliographic Details
Published in:World journal of gastrointestinal surgery 2010-10, Vol.2 (10), p.342-346
Main Authors: Salvia, Roberto, Crippa, Stefano, Partelli, Stefano, Armatura, Giulia, Malleo, Giuseppe, Paini, Marina, Pea, Antonio, Bassi, Claudio
Format: Article
Language:English
Subjects:
Branch-duct
Combined
Followup
Intraductal
Main-duct
Malignancy
mucinous
neoplasms
Nodules
papillary
Surgery
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Summary:In the last decade,intraductal papillary mucinous neoplasms(IPMNs) have become commonly diagnosed.From a morphological standpoint,they are classified in main-duct IPMNs(MD-IPMNs) and branch-duct IPMNs(BD-IPMNs),depending on the type of involvement of the pancreatic ductal system by the neoplasm.Despite the fact that our understanding of their natural history is still incomplete,recent data indicate that MD-IPMNs and BD-IPMNs show significant differences in terms of biological behaviour with MD-IPMNs at higher risk of malignant degeneration.In the present paper,clinical and epidemiological characteristics,rates of malignancy and the natural history of MD-IPMNs and BD-IPMNs are analyzed.The profile of IPMNs involving both the main pancreatic duct and its side branches(combined-IPMNs) are also discussed.Finally,general recommendations for management based on these differences are given.
ISSN:1948-9366
1948-9366
DOI:10.4240/wjgs.v2.i10.342