Less discontinuation of ADHD drug use since the availability of long-acting ADHD medication in children, adolescents and adults under the age of 45 years in the Netherlands

Treatment options for ADHD in the Netherlands have increased with the introduction of the extended-release formulations of methylphenidate (MPH ER, Concerta ® ) in 2003 and atomoxetine (ATX, Strattera ® ) in 2005, but data on the effect on drug usage patterns are scarce. The objective of the present...

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Bibliographic Details
Published in:Attention deficit and hyperactivity disorders 2010-12, Vol.2 (4), p.213-220
Main Authors: van den Ban, Els, Souverein, Patrick C., Swaab, Hanna, van Engeland, Herman, Egberts, Toine C. G., Heerdink, Eibert R.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Atomoxetine Hydrochloride
Attention Deficit Disorder with Hyperactivity - drug therapy
Central Nervous System Stimulants - administration & dosage
Central Nervous System Stimulants - therapeutic use
Child
Child, Preschool
Community Pharmacy Services - statistics & numerical data
Delayed-Action Preparations - therapeutic use
Drug Utilization - statistics & numerical data
Drug Utilization - trends
Female
Humans
Infant
Male
Medicine
Medicine & Public Health
Methylphenidate - administration & dosage
Methylphenidate - therapeutic use
Middle Aged
Netherlands
Original
Original Article
Propylamines - administration & dosage
Propylamines - therapeutic use
Psychiatry
Sex Characteristics
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Summary:Treatment options for ADHD in the Netherlands have increased with the introduction of the extended-release formulations of methylphenidate (MPH ER, Concerta ® ) in 2003 and atomoxetine (ATX, Strattera ® ) in 2005, but data on the effect on drug usage patterns are scarce. The objective of the present study was to describe changes in the patterns of ADHD medication use and determinants thereof among children, adolescents and adults (18 years. After the introduction of MPH ER and ATX (time cohort III), 16.5% of the incident ADHD drug users switched their medication and almost 9% added an ADHD drug to the prior ADHD drug. In conclusion, discontinuation of incident ADHD drug use is high after 3, 6 and 12 months. During the study period, the incidence of discontinuation decreased because of the availability of extended-release methylphenidate and atomoxetine.
ISSN:1866-6116
1866-6647
DOI:10.1007/s12402-010-0044-9