Performance Characteristics of BGO Detectors for a Low Cost Preclinical PET Scanner

• Published in: IEEE transactions on nuclear science 2010-06, Vol.57 (3), p.1038-1044
• Main Authors: Zhang, H, Vu, N T, Bao, Q, Silverman, R W, Berry-Pusey, B N, Douraghy, A, Williams, D A, Rannou, F R, Stout, D B, Chatziioannou, A F
• Format: Article
• Language: English
• Subjects: Arrays; BGO (crystal); Bismuth; Bismuth germanate (BGO) scintillator; Costs; Crystals; detector; Detectors; Energy resolution; Event detection; Head; Low cost; Polyethylene terephthalates; Positron emission tomography; positron emission tomography (PET); Scanners; Sensor arrays; small animal imaging; Spatial resolution; Studies; Throughput
• ISSN: 0018-9499; 1558-1578
• DOI: 10.1109/TNS.2010.2046753

PETbox is a low-cost benchtop PET scanner dedicated to high throughput preclinical imaging that is currently under development at our institute. This paper presents the design and characterization of the detectors that are used in the PETbox system. In this work, bismuth germanate scintillator was used for the detector, taking advantage of its high stopping power, high photoelectric event fraction, lack of intrinsic background radiation and low cost. The detector block was segmented into a pixelated array consisting of 20 × 44 elements, with a crystal pitch of 2.2 mm and a crystal cross section of 2 mm × 2 mm. The effective area of the array was 44 mm × 96.8 mm. The array was coupled to two Hamamatsu H8500 position sensitive photomultiplier tubes, forming a flat-panel type detector head with a sensitive area large enough to cover the whole body of a typical laboratory mouse. Two such detector heads were constructed and their performance was characterized. For one detector head, the energy resolution ranged from 16.1% to 38.5% full width at half maximum (FWHM), with a mean of 20.1%; for the other detector head, the energy resolution ranged from 15.5% to 42.7% FWHM, with a mean of 19.6 %. The intrinsic spatial resolution was measured to range from 1.55 mm to 2.39 mm FWHM along the detector short axis and from 1.48 mm to 2.33 mm FWHM along the detector long axis, with an average of 1.78 mm. Coincidence timing resolution for the detector pair was measured to be 4.1 ns FWHM. These measurement results show that the detectors are suitable for our specific application.