Neonatal hyperthyroidism associated with isolated submandibular sialadenitis: is it just a coincidence?

Isolated submandibular sialadenitis is extremely rare in the neonatal period. All reported cases had predisposing factors such as prematurity, dehydration, anatomic deformities, calculi, and long-term oro-gastric tube feeding. Here, we present a case of neonatal isolated submandibular sialadenitis w...

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Bibliographic Details
Published in:Journal of clinical research in pediatric endocrinology 2010-03, Vol.2 (1), p.43-45
Main Authors: Uckun Kitapci, Aysin, Suha Calikoglu, Ali
Format: Article
Language:English
Subjects:
Case Reports
Female
Graves Disease - complications
Humans
Hyperthyroidism - complications
Infant, Newborn
Infant, Newborn, Diseases
Male
Pregnancy
Pregnancy Complications
Sialadenitis - complications
Submandibular Gland Diseases - complications
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Summary:Isolated submandibular sialadenitis is extremely rare in the neonatal period. All reported cases had predisposing factors such as prematurity, dehydration, anatomic deformities, calculi, and long-term oro-gastric tube feeding. Here, we present a case of neonatal isolated submandibular sialadenitis without any known risk factors and who was diagnosed later with hyperthyroidism secondary to maternal Graves' disease. Both sialadenitis and hyperthyroidism resolved with appropriate treatment. While both conditions are rare and important in neonatal emergency care, the possibility of neonatal hyperthyroidism should be explored in cases with isolated sialadenitis if there is no other risk factor. Possible mechanisms for this uncommon association are discussed.
ISSN:1308-5727
1308-5735
DOI:10.4274/jcrpe.v2i1.43