Patients with Acinetobacter baumannii bloodstream infections are colonized in the gastrointestinal tract with identical strains

In this study, we identified critically ill patients with Acinetobacter baumannii bacteremia and examined perirectal surveillance cultures for the presence of genetically related A baumannii strains using pulsed-field gel electrophoresis to determine whether gut colonization preceded clinical infect...

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Bibliographic Details
Published in:American journal of infection control 2010-11, Vol.38 (9), p.751-753
Main Authors: Thom, Kerri A., MD, MS, Hsiao, William W.L., PhD, Harris, Anthony D., MD, MPH, Stine, O. Colin, PhD, Rasko, David A., PhD, Johnson, J. Kristie, PhD
Format: Article
Language:English
Subjects:
Acinetobacter baumannii
Acinetobacter baumannii - classification
Acinetobacter baumannii - drug effects
Acinetobacter baumannii - isolation & purification
Acinetobacter Infections - microbiology
Adult
Aged
Anti-Bacterial Agents - pharmacology
Antibiotics
Bacteremia - microbiology
Bacterial diseases
Bacterial infections
Bacterial sepsis
Bacterial Typing Techniques
beta-Lactam Resistance
Biological and medical sciences
Blood - microbiology
Clinical medicine
Critical Illness
Cross Infection - microbiology
DNA Fingerprinting
Drug resistance
Electrophoresis, Gel, Pulsed-Field
Epidemiology. Vaccinations
Female
Gastroenterology
Gastrointestinal diseases
Gastrointestinal Tract - microbiology
General aspects
hospital epidemiology
Human bacterial diseases
Humans
Imipenem - pharmacology
Infection Control
Infectious Disease
Infectious diseases
Male
Medical sciences
Middle Aged
Molecular Epidemiology
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Description
Summary:In this study, we identified critically ill patients with Acinetobacter baumannii bacteremia and examined perirectal surveillance cultures for the presence of genetically related A baumannii strains using pulsed-field gel electrophoresis to determine whether gut colonization preceded clinical infection. Seven patients with imipenem-resistant A baumannii bacteremia were identified from January to June of 2008. Six of 7 (86%) patients were colonized in the gastrointestinal tract with genetically similar strains preceding their bacteremia.
ISSN:0196-6553
1527-3296
DOI:10.1016/j.ajic.2010.03.005