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Obstetric outcomes after treatment of periodontal disease during pregnancy: systematic review and meta-analysis

Objective To examine whether treatment of periodontal disease with scaling and root planing during pregnancy is associated with a reduction in the preterm birth rate.Design Systematic review and meta-analysis of randomised controlled trials.Data sources Cochrane Central Trials Registry, ISI Web of S...

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Bibliographic Details
Published in:BMJ 2010-12, Vol.341 (7788), p.91-91
Main Authors: Polyzos, Nikolaos P, Polyzos, Ilias P, Zavos, Apostolos, Valachis, Antonis, Mauri, Davide, Papanikolaou, Evangelos G, Tzioras, Spyridon, Weber, Daniel, Messinis, Ioannis E
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Language:English
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Summary:Objective To examine whether treatment of periodontal disease with scaling and root planing during pregnancy is associated with a reduction in the preterm birth rate.Design Systematic review and meta-analysis of randomised controlled trials.Data sources Cochrane Central Trials Registry, ISI Web of Science, Medline, and reference lists of relevant studies to July 2010; hand searches in key journals.Study selection Randomised controlled trials including pregnant women with documented periodontal disease randomised to either treatment with scaling and root planing or no treatment.Data extraction Data were extracted by two independent investigators, and a consensus was reached with the involvement a third. Methodological quality of the studies was assessed with the Cochrane’s risk of bias tool, and trials were considered either high or low quality. The primary outcome was preterm birth (
ISSN:0959-8138
0959-535X
1468-5833
1756-1833
DOI:10.1136/bmj.c7017