Relation of QRS Width in Healthy Persons to Risk of Future Permanent Pacemaker Implantation

In the setting of acute myocardial infarction, prolongation of the QRS interval on electrocardiography identifies patients at risk for needing permanent pacemaker implantation. However, the implications of prolonged QRS intervals in healthy subjects are unclear, especially given that the QRS prolong...

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Bibliographic Details
Published in:The American journal of cardiology 2010-09, Vol.106 (5), p.668-672
Main Authors: Cheng, Susan, MD, Larson, Martin G., ScD, Keyes, Michelle J., PhD, McCabe, Elizabeth L., MS, Newton-Cheh, Christopher, MD, MPH, Levy, Daniel, MD, Benjamin, Emelia J., MD, ScM, Vasan, Ramachandran S., MD, Wang, Thomas J., MD
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Bundle-Branch Block - diagnosis
Bundle-Branch Block - epidemiology
Bundle-Branch Block - therapy
Cardiac Pacing, Artificial
Cardiology
Cardiology. Vascular system
Cardiovascular
Case-Control Studies
Clinical medicine
Cohort Studies
Electrocardiography
Female
Health risk assessment
Heart
Heart failure
Humans
Incidence
Male
Medical sciences
Middle Aged
Pacemaker, Artificial
Proportional Hazards Models
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Risk Assessment
Severity of Illness Index
Young Adult
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Description
Summary:In the setting of acute myocardial infarction, prolongation of the QRS interval on electrocardiography identifies patients at risk for needing permanent pacemaker implantation. However, the implications of prolonged QRS intervals in healthy subjects are unclear, especially given that the QRS prolongation encountered in this setting is typically mild. The aim of this study was to assess the relation between QRS duration and incident pacemaker implantation in a community-based cohort of 8,311 subjects (mean age 54 years, 55% women) who attended 17,731 routine examinations with resting 12-lead electrocardiography. QRS duration was analyzed as a continuous and a categorical variable (
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2010.04.021