Bronchial associated lymphoid tissue (BALT) lymphoma presenting as chronic lung sepsis

A 58-year-old woman was referred from her general practitioner to the respiratory clinic with a 2 year history of recurrent pulmonary infections, mucus hypersecretion and right lobe consolidation following a severe pneumonic illness in 2006. She had no significant risk factors for respiratory diseas...

Full description

Saved in:
Bibliographic Details
Published in:BMJ case reports 2009, Vol.2009 (sep06 2), p.bcr0320091716-bcr0320091716
Main Authors: Hoeritzauer, Anne Ingrid, Venkatraman, Laskshmi, Manus, Kieran Mc, Kettle, Paul, Sah, Shatrugan, Elborn, Stuart
Format: Article
Language:English
Subjects:
Biopsy
Bone marrow
Case reports
Disease
Dyspnea
Etiology
Europe (West)
Female
Histology
Immune system
Immunoglobulins
Infections
Lymphatic system
Lymphocytes
Lymphoma
Medical imaging
Patients
Pleural effusion
Proteins
Quality of life
Radiation therapy
Reminder of Important Clinical Lesson
Sepsis
Thoracic surgery
Tomography
Tuberculosis
White
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 58-year-old woman was referred from her general practitioner to the respiratory clinic with a 2 year history of recurrent pulmonary infections, mucus hypersecretion and right lobe consolidation following a severe pneumonic illness in 2006. She had no significant risk factors for respiratory disease. Chest computed tomography showed an air bronchogram and right lower lobe consolidation. On initial routine investigation IgA and IgG were normal; however, a discrete IgM paraprotein band in the mid gamma region was seen on serum electrophoresis. She was referred for haematological investigations. Bone marrow biopsy was positive for monoclonal lymphoplasmocytoid B cells and the patient was diagnosed with Waldenström’s macroglobulinaemia. Due to recurrent infections and an unclear diagnosis of the lung process, a right lower lobectomy and wedge resection of the middle lobe was performed. This showed bronchial associated lymphoid tissue lymphoma arising in the marginal zone. She has been well since surgery with no further respiratory infections.
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr.03.2009.1716