Clinicopathologic and immunophenotypic study of non-Hodgkin's lymphoma in Korea. Lymphoreticular Study Group of the Korean Society of Pathologists

• Published in: Journal of Korean medical science 1992-09, Vol.7 (3), p.193-198
• Main Authors: Kim, C W, Kim, I, Ko, Y H, Cho, H, Yang, W I, Kwon, G Y, Lee, D G, Moon, H B, Suh, C H, Juhng, S W
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Humans; Immunophenotyping; Korea; Lymphoma, Non-Hodgkin - classification; Lymphoma, Non-Hodgkin - immunology; Lymphoma, Non-Hodgkin - pathology; Male; Middle Aged
• ISSN: 1011-8934; 1598-6357
• DOI: 10.3346/jkms.1992.7.3.193

This study sponsored by the Lymphoreticular Study Group of the Korean Society of Pathologists was carried out to provide nationwide data about the histopathologic-immunophenotypic features of malignant lymphomas in Korea. Two hundred and ninety Non-Hodgkin's lymphoma (NHL) among 312 malignant lymphomas collected from three representative areas in Korea were histologically reclassified. Two hundred and fifty three cases were immunohistochemically studied. T-cell lymphoma comprised 35.2% of NHL in this study and showed a quite comparable incidence to that of Japan and China, but it was much higher than in Western countries. A very low prevalence rate of the follicular variety (4.0%) and a higher propensity of primary extranodal involvement (60%) are additional characteristics of NHL in Korea. The most common histologic subtype of B cell lymphoma was diffuse large cell type, whereas the most common subtype of T cell lymphoma was diffuse mixed small and large cell type.