Beneficial Regulation of Matrix Metalloproteinases for Skin Health

Matrix metalloproteinases (MMPs) are essential to the remodeling of the extracellular matrix. While their upregulation facilitates aging and cancer, they are essential to epidermal differentiation and the prevention of wound scars. The pharmaceutical industry is active in identifying products that i...

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Bibliographic Details
Published in:Enzyme Research 2011-03, Vol.2011 (2011), p.396-399
Main Authors: Philips, Neena, Auler, Susan, Hugo, Raul, GonzÃlez, Salvador
Format: Article
Language:English
Subjects:
Extracellular matrix
Physiological aspects
Proteases
Review
Skin
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Summary:Matrix metalloproteinases (MMPs) are essential to the remodeling of the extracellular matrix. While their upregulation facilitates aging and cancer, they are essential to epidermal differentiation and the prevention of wound scars. The pharmaceutical industry is active in identifying products that inhibit MMPs to prevent or treat aging and cancer and products that stimulate MMPs to prevent epidermal hyperproliferative diseases and wound scars.
ISSN:2090-0414
2090-0406
2090-0414
DOI:10.4061/2011/427285