Application of the Beauveria bassiana Strain for the Enantioselective Oxidation of the Diethyl 1-Hydroxy-1-Phenylmethanephosphonate

Biotransformation of diethyl 1-hydroxy-1-phenylmethanephosphonate using fungi Beauveria bassiana allowed resolving the racemic mixture of the substrate and due to the biocatalyst and reaction conditions modifications, leading to desired optical isomer.

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Bibliographic Details
Published in:Current microbiology 2011-04, Vol.62 (4), p.1168-1172
Main Authors: Żymańczyk-Duda, Ewa, Brzezińska-Rodak, Małgorzata, Klimek-Ochab, Magdalena, Lejczak, Barbara
Format: Article
Language:English
Subjects:
Beauveria - chemistry
Beauveria - metabolism
Beauveria bassiana
biocatalysts
Biomedical and Life Sciences
Biotechnology
Biotransformation
Catalysts
Enantiomers
Fungi
Isomers
Life Sciences
Microbiology
Organophosphonates - chemistry
Organophosphonates - metabolism
Oxidation
Oxidation-Reduction
Stereoisomerism
Substrates
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Description
Summary:Biotransformation of diethyl 1-hydroxy-1-phenylmethanephosphonate using fungi Beauveria bassiana allowed resolving the racemic mixture of the substrate and due to the biocatalyst and reaction conditions modifications, leading to desired optical isomer.
ISSN:0343-8651
1432-0991
DOI:10.1007/s00284-010-9840-x