Lipid-soluble vitamins A, D, and E in HIV-infected pregnant women in Tanzania

• Published in: European journal of clinical nutrition 2010-08, Vol.64 (8), p.808-817
• Main Authors: Mehta, S, Spiegelman, D, Aboud, S, Giovannucci, E L, Msamanga, G I, Hertzmark, E, Mugusi, F M, Hunter, D J, Fawzi, W W
• Format: Article
• Language: English
• Subjects: 631/443/494; 692/699/1702/295; 692/699/255/1901; 692/700/459/1994; Adolescent; Adult; Alfacalcidol; Anemia; Anemia, Iron-Deficiency - epidemiology; Anemia, Iron-Deficiency - etiology; Avitaminosis - blood; Avitaminosis - complications; Avitaminosis - epidemiology; Biological and medical sciences; Blood Sedimentation; Calcifediol; Calciferol; CD8 antigen; CD8-Positive T-Lymphocytes - metabolism; Cell Count; Clinical Nutrition; Confidence intervals; Correlation; Diet - economics; Dietary supplements; Epidemiology; Erythrocyte sedimentation rate; Erythrocytes; Feeding. Feeding behavior; Female; Food and nutrition; Fundamental and applied biological sciences. Psychology; Gestational Age; Health aspects; Hemoglobin; Hemoglobins - metabolism; HIV; HIV Infections - blood; HIV Infections - complications; HIV patients; Human immunodeficiency virus; Human viral diseases; Humans; Infectious diseases; Internal Medicine; Lipids; Low concentrations; Medical sciences; Medicine; Medicine & Public Health; Metabolic Diseases; Nutritional Status; original-article; Parameter identification; Plasma; Pregnancy; Pregnant women; Prenatal care; Prevalence; Public Health; Regression Analysis; Retinene; Selenium; Selenium - blood; Signs and symptoms; Statistical analysis; Tanzania - epidemiology; Tocopherol; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Vitamin A; Vitamin A - blood; Vitamin A Deficiency - blood; Vitamin A Deficiency - complications; Vitamin A Deficiency - epidemiology; Vitamin D; Vitamin D - blood; Vitamin D Deficiency - blood; Vitamin D Deficiency - complications; Vitamin D Deficiency - epidemiology; Vitamin deficiency; Vitamin E; Vitamin E - blood; Vitamin E Deficiency - blood; Vitamin E Deficiency - complications; Vitamin E Deficiency - epidemiology; Vitamins; Young Adult
• ISSN: 0954-3007; 1476-5640
• DOI: 10.1038/ejcn.2010.76

Background/Objectives: There is limited published research examining lipid-soluble vitamins in human immunodeficiency virus (HIV)-infected pregnant women, particularly in resource-limited settings. Subjects/Methods: This is an observational analysis of 1078 HIV-infected pregnant women enrolled in a trial of vitamin supplementation in Tanzania. Baseline data on sociodemographic and anthropometric characteristics, clinical signs and symptoms, and laboratory parameters were used to identify correlates of low plasma vitamin A (