Chronic Fine Particulate Matter Exposure Induces Systemic Vascular Dysfunction via NADPH Oxidase and TLR4 Pathways

RATIONALE:Chronic exposure to ambient air-borne particulate matter of

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Bibliographic Details
Published in:Circulation research 2011-03, Vol.108 (6), p.716-726
Main Authors: Kampfrath, Thomas, Maiseyeu, Andrei, Ying, Zhekang, Shah, Zubair, Deiuliis, Jeffrey A, Xu, Xiaohua, Kherada, Nisharahmed, Brook, Robert D, Reddy, Kongara M, Padture, Nitin P, Parthasarathy, Sampath, Chen, Lung Chi, Moffatt-Bruce, Susan, Sun, Qinghua, Morawietz, Henning, Rajagopalan, Sanjay
Format: Article
Language:English
Subjects:
Administration, Inhalation
Air Pollutants - adverse effects
Animals
Biological and medical sciences
Environmental Exposure
Enzyme Activation
Fundamental and applied biological sciences. Psychology
Inflammation - etiology
Lung - metabolism
Male
Mice
Mice, Inbred Strains
Mice, Knockout
Mice, Transgenic
NADPH Oxidases - metabolism
Oxidation-Reduction
Particle Size
Particulate Matter - administration & dosage
Particulate Matter - adverse effects
Phospholipids - metabolism
Time Factors
Toll-Like Receptor 4 - metabolism
Vascular Diseases - chemically induced
Vascular Diseases - etiology
Vertebrates: cardiovascular system
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Description
Summary:RATIONALE:Chronic exposure to ambient air-borne particulate matter of
ISSN:0009-7330
1524-4571
DOI:10.1161/CIRCRESAHA.110.237560