Pharmacologic modulation of experimentally induced allergic asthma

Allergic asthma is the most frequent disease of the respiratory tract. The aim of the current experimental and clinical studies was to find new sources of drugs able to control asthmatic inflammation and airway hyperresponsiveness. Our experimental studies were focused on efficiency evaluation of su...

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Bibliographic Details
Published in:Interdisciplinary toxicology 2011-03, Vol.4 (1), p.27-32
Main Authors: Fraňová, Soňa, Strapková, Anna, Mokrý, Juraj, Šutovská, Martina, Jošková, Marta, Sadloňová, Vladimíra, Antošová, Martina, Pavelčíková, Darina, Flešková, Dana, Nosáľová, Gabriela
Format: Article
Language:English
Subjects:
allergic asthma
Allergies
Asthma
ion channels
nitric oxide
PDE
Polyphenols
Review
Toxicology
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Summary:Allergic asthma is the most frequent disease of the respiratory tract. The aim of the current experimental and clinical studies was to find new sources of drugs able to control asthmatic inflammation and airway hyperresponsiveness. Our experimental studies were focused on efficiency evaluation of substances able to influence activities of ion channels, phosphodiesterase (PDE) isoforms, substances from the group of polyphenols and NO metabolism modulators during experimentally induced allergic asthma.
ISSN:1337-6853
1337-9569
DOI:10.2478/v10102-011-0006-x