CT of the hips in the investigation of protrusio acetabuli in Marfan syndrome. A case control study

Objectives To establish the prevalence of protrusio acetabuli (PA) in adults fulfilling the Ghent criteria for Marfan syndrome (MFS), and in a normal adult population. Methods 105 adults with probable MFS and 107 controls were included. CT of the hips was obtained. A qualitative assessment of PA was...

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Bibliographic Details
Published in:European radiology 2011-07, Vol.21 (7), p.1485-1491
Main Authors: Lundby, Rigmor, Kirkhus, Eva, Rand-Hendriksen, Svend, Hald, John, Pripp, Are Hugo, Smith, Hans-Jørgen
Format: Article
Language:English
Subjects:
Acetabulum - abnormalities
Acetabulum - diagnostic imaging
Adult
Adults
Aged
Analysis of Variance
Case-Control Studies
Chi-Square Distribution
Coronary vessels
Diagnostic Radiology
Female
Hospitals
Humans
Imaging
Internal Medicine
Interventional Radiology
Male
Marfan syndrome
Marfan Syndrome - diagnostic imaging
Marfan Syndrome - physiopathology
Medicine
Medicine & Public Health
Middle Aged
Musculoskeletal
Musculoskeletal Abnormalities - diagnostic imaging
Neuroradiology
Pulmonary arteries
Radiology
ROC Curve
Scandals
Tomography
Tomography, X-Ray Computed - methods
Ultrasound
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Summary:Objectives To establish the prevalence of protrusio acetabuli (PA) in adults fulfilling the Ghent criteria for Marfan syndrome (MFS), and in a normal adult population. Methods 105 adults with probable MFS and 107 controls were included. CT of the hips was obtained. A qualitative assessment of PA was performed. A new method for estimating the degree of PA was introduced with measurement of the parameter CWD (circle-wall distance). Results were compared to an alternative method based on MRI [ 1 ]. Results 87 of the study group fulfilled the Ghent criteria of MFS (Ghent positives), and 18 did not (Ghent negatives). PA was diagnosed qualitatively in 74.7% of Ghent positive persons, in 27.8% of Ghent negative persons, and in 3.7% of the controls. CWD was significantly different between the three groups ( p  
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-011-2073-y