Cutaneous granular cell tumor of the breast: a clinical diagnostic pitfall

We report the clinical-morphological study of a granular cell tumor in dermal/hypodermal junction and subcutaneous fat left breast of an 83-year-old woman with a family history of breast carcinoma. Mammography study showed a spiculated lesion in the lower inner quadrant with suspicion of malignancy....

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Published in:Journal of clinical medicine research 2010-08, Vol.2 (4), p.185-188
Main Authors: Aneiros-Fernandez, Jose, Arias-Santiago, Salvador, Husein-Elahmed, Husein, Ovalle, Francisco, Siendones, Maria Ines Aroca, Aneiros-Cachaza, Jose
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Case Report
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container_issue 4
container_start_page 185
container_title Journal of clinical medicine research
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creator Aneiros-Fernandez, Jose
Arias-Santiago, Salvador
Husein-Elahmed, Husein
Ovalle, Francisco
Siendones, Maria Ines Aroca
Aneiros-Cachaza, Jose
description We report the clinical-morphological study of a granular cell tumor in dermal/hypodermal junction and subcutaneous fat left breast of an 83-year-old woman with a family history of breast carcinoma. Mammography study showed a spiculated lesion in the lower inner quadrant with suspicion of malignancy. The results of fine needle puncture-aspiration were inconclusive. Subsequent tumorectomy revealed a poorly-defined indurated lesion of 1.1 x 0.7 cm. The histopathology study showed a proliferation of cells with ample and granular cytoplasm that were positive for S100, CD 68 and inhibin and negative for hormonal receptors. We present a benign lesion that clinically reproduces a breast carcinoma. Granular cell tumor; Breast; Differential diagnosis; Cutaneous.
doi_str_mv 10.4021/jocmr403w
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title Cutaneous granular cell tumor of the breast: a clinical diagnostic pitfall
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