What is flux balance analysis?

Flux balance analysis is a mathematical approach for analyzing the flow of metabolites through a metabolic network. This primer covers the theoretical basis of the approach, several practical examples and a software toolbox for performing the calculations.

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Bibliographic Details
Published in:Nature biotechnology 2010-03, Vol.28 (3), p.245-248
Main Authors: Palsson, Bernhard Ø, Orth, Jeffrey D, Thiele, Ines
Format: Article
Language:English
Subjects:
631/114/2390
631/443/319
631/61
Agriculture
Bioinformatics
Biological and medical sciences
Biomass
Biomedical and Life Sciences
Biomedical Engineering/Biotechnology
Biomedicine
Biotechnology
Escherichia coli - metabolism
Fundamental and applied biological sciences. Psychology
General aspects
Life Sciences
Mathematical analysis
Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects)
Metabolic Networks and Pathways
Metabolites
Models, Biological
Oxygen - metabolism
Phenotype
primer
Systems Biology - methods
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Description
Summary:Flux balance analysis is a mathematical approach for analyzing the flow of metabolites through a metabolic network. This primer covers the theoretical basis of the approach, several practical examples and a software toolbox for performing the calculations.
ISSN:1087-0156
1546-1696
DOI:10.1038/nbt.1614