Effective use of polymyxin B hemoperfusion in septic shock complicated by urosepsis

Direct hemoperfusion using polymyxin B-immobilized fiber (PMX-DHP) is an established treatment method for septic shock caused by Gram-negative infections. Here we report one instance in which PMX-DHP therapy has been used successfully in a patient with septic shock from urosepsis. After antibiotic t...

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Bibliographic Details
Published in:Indian journal of nephrology 2011-01, Vol.21 (1), p.41-43
Main Authors: Malleshappa, P, Ranganath, R, Chaudhari, A P, Singhai, P, Aghariya, M, Shah, A B
Format: Article
Language:English
Subjects:
Antibiotics
Bacterial infections
Blood pressure
Cardiac patients
Care and treatment
Case Report
Case studies
Confidence intervals
Diseases
Dopamine
Drug therapy
E coli
Health aspects
Mortality
Polymyxin B
Risk factors
Sepsis
Septic shock
Ventilation
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Summary:Direct hemoperfusion using polymyxin B-immobilized fiber (PMX-DHP) is an established treatment method for septic shock caused by Gram-negative infections. Here we report one instance in which PMX-DHP therapy has been used successfully in a patient with septic shock from urosepsis. After antibiotic therapy, direct hemoperfusion using polymyxin B helped in cardiovascular stability. The patient recovered from the shock within a few days after treatment with polymyxin-B hemoperfusion. As far as we are aware, this is the first reported case of effective treatment of urosepsis complicated by septic shock using PMX-DHP therapy in India.
ISSN:0971-4065
1998-3662
DOI:10.4103/0971-4065.78077