Solitary hepatic gastrinoma treated with laparoscopic radiofrequency ablation

This is a case of a solitary hepatic gastrinoma in a 65-year-old male. The patient was diagnosed with Zollinger-Ellison syndrome in 1991. He had negative radiologic and surgical explorations at that time. He was maintained on proton-pump inhibitors for the next 10 years without symptoms. A computed...

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Bibliographic Details
Published in:Journal of the Society of Laparoendoscopic Surgeons 2003-07, Vol.7 (3), p.285-289
Main Authors: Deol, Zöe K, Frezza, Eldo, DeJong, Steven, Pickleman, Jack
Format: Article
Language:English
Subjects:
Aged
Case Reports
Catheter Ablation
Gastrinoma - surgery
Humans
Laparoscopy
Liver Neoplasms - surgery
Male
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Summary:This is a case of a solitary hepatic gastrinoma in a 65-year-old male. The patient was diagnosed with Zollinger-Ellison syndrome in 1991. He had negative radiologic and surgical explorations at that time. He was maintained on proton-pump inhibitors for the next 10 years without symptoms. A computed tomographic (CT) scan done in April 2001 demonstrated a 5-cm right hepatic lesion. Radionucleotide scanning with octreotide demonstrated intense activity in the same area in the right hepatic lobe. His serum gastrin was 317 pg/mL. He underwent laparoscopic radiofrequency ablation of the lesion. Treatment resulted in a 6-cm ablative area giving a 1-cm margin on the tumor. One- and 3-month follow-up CT scans demonstrated adequate ablation of the tumor. An octreotide scan done 3 months postoperatively did not reveal any areas of abnormal uptake. We report success with laparoscopic radiofrequency ablation as an alternative to major hepatic resection in patients with a solitary hepatic gastrinoma.
ISSN:1086-8089
1938-3797