Clinical efficacy of percutaneous renal revascularization with stent placement in hypertension among patients with atherosclerotic renovascular diseases

Aim: The aim was to assess the effect of renal angioplasty with stent on systolic, diastolic, and mean arterial blood pressure (MAP) in awake and sleep time with ambulatory blood pressure (ABP) monitoring (Holter monitoring). Materials and Methods Patients with angiographically proven atheroscleroti...

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Bibliographic Details
Published in:Journal of cardiovascular disease research 2011-01, Vol.2 (1), p.36-43
Main Authors: Adel, Seyed Mohammad Hassan, Syeidian, Seyed Masood, Najafi, Mohammad, nourizadeh, Mohammad
Format: Article
Language:English
Subjects:
Ambulatory blood pressure
Angiography
Angioplasty
atherosclerosis
Care and treatment
Diagnosis
Drug therapy
Health aspects
Hypertension
Medical imaging
Original
Renovascular hypertension
Risk factors
Stent (Surgery)
Surgery
Veins & arteries
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Summary:Aim: The aim was to assess the effect of renal angioplasty with stent on systolic, diastolic, and mean arterial blood pressure (MAP) in awake and sleep time with ambulatory blood pressure (ABP) monitoring (Holter monitoring). Materials and Methods Patients with angiographically proven atherosclerotic renal artery stenosis (RAS) were referred to the Angiography Department of Imam Hospital for intervention during a 1-year period from June 2008 to December 2009. Primary stent placement was attempted by a single operator in 27 severe RAS cases although 1 case was omitted from the study because of technical failure. Pre- and postprocedure creatinine levels, ejection fraction (EF), history of diabetes mellitus (DM), and ABP were obtained. Twenty-six (17 men, 9 women; average age, 62.6 years; age range, 90-21 years) consecutive patients participated in the study. Results: All patients had severe hypertension resistant to multiple medications; 10 patients had impaired renal fonction (serum creatinine level greater than 130μmol/L). A total of 3 (11.5%) patients had congestive heart failure, and 10 (37.7%) were diabetic. Hypertension was cured in 1 (4%) patient, had improved in 23 (88.4%) patients, and had failed to respond to treatment in 2 (7.6%). Serum creatinine decreased significantly from 1.46±0.89 to 1.35±0.61mg/dL (P
ISSN:0975-3583
0976-2833
DOI:10.4103/0975-3583.78585