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Getting Closer to the Dirty Little Secret
The molecular mechanism behind alum adjuvanticity is probably the oldest secret of immunology. In this issue of Immunity, Kuroda et al. (2011) and Kool et al. (2011) identify NLRP3 inflammasome-independent signaling to be crucial for the Th2 cell response induced by aluminum salts.
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Published in: | Immunity (Cambridge, Mass.) Mass.), 2011-04, Vol.34 (4), p.455-458 |
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Main Authors: | , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | The molecular mechanism behind alum adjuvanticity is probably the oldest secret of immunology. In this issue of
Immunity,
Kuroda et al. (2011) and
Kool et al. (2011) identify NLRP3 inflammasome-independent signaling to be crucial for the Th2 cell response induced by aluminum salts. |
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ISSN: | 1074-7613 1097-4180 |
DOI: | 10.1016/j.immuni.2011.04.003 |