Micro Electromechanical Systems (MEMS) Based Microfluidic Devices for Biomedical Applications

Micro Electromechanical Systems (MEMS) based microfluidic devices have gained popularity in biomedicine field over the last few years. In this paper, a comprehensive overview of microfluidic devices such as micropumps and microneedles has been presented for biomedical applications. The aim of this p...

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Bibliographic Details
Published in:International journal of molecular sciences 2011-06, Vol.12 (6), p.3648-3704
Main Authors: Ashraf, Muhammad Waseem, Tayyaba, Shahzadi, Afzulpurkar, Nitin
Format: Article
Language:English
Subjects:
Biocompatible Materials - chemistry
Drug Delivery Systems
Humans
Micro-Electrical-Mechanical Systems
Microfluidic Analytical Techniques - instrumentation
Microinjections
Review
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Summary:Micro Electromechanical Systems (MEMS) based microfluidic devices have gained popularity in biomedicine field over the last few years. In this paper, a comprehensive overview of microfluidic devices such as micropumps and microneedles has been presented for biomedical applications. The aim of this paper is to present the major features and issues related to micropumps and microneedles, e.g., working principles, actuation methods, fabrication techniques, construction, performance parameters, failure analysis, testing, safety issues, applications, commercialization issues and future prospects. Based on the actuation mechanisms, the micropumps are classified into two main types, i.e., mechanical and non-mechanical micropumps. Microneedles can be categorized according to their structure, fabrication process, material, overall shape, tip shape, size, array density and application. The presented literature review on micropumps and microneedles will provide comprehensive information for researchers working on design and development of microfluidic devices for biomedical applications.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms12063648