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An ecologic analysis of county-level PM2.5 concentrations and lung cancer incidence and mortality
Few studies have explored the relationship between PM2.5 and lung cancer incidence. Although results are mixed, some studies have demonstrated a positive relationship between PM2.5 and lung cancer mortality. Using an ecologic study design, we examined the county-level associations between PM2.5 conc...
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Published in: | International journal of environmental research and public health 2011-06, Vol.8 (6), p.1865-1871 |
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container_title | International journal of environmental research and public health |
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creator | Vinikoor-Imler, Lisa C Davis, J Allen Luben, Thomas J |
description | Few studies have explored the relationship between PM2.5 and lung cancer incidence. Although results are mixed, some studies have demonstrated a positive relationship between PM2.5 and lung cancer mortality. Using an ecologic study design, we examined the county-level associations between PM2.5 concentrations (2002-2005) and lung cancer incidence and mortality in North Carolina (2002-2006). Positive trends were observed between PM2.5 concentrations and lung cancer incidence and mortality; however, the R2 for both were |
doi_str_mv | 10.3390/ijerph8061865 |
format | article |
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Although variability is high, thus reflecting the importance of tobacco smoking and other etiologic agents that influence lung cancer incidence and mortality besides PM2.5, a positive trend is observed between PM2.5 and lung cancer incidence and mortality. 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Although results are mixed, some studies have demonstrated a positive relationship between PM2.5 and lung cancer mortality. Using an ecologic study design, we examined the county-level associations between PM2.5 concentrations (2002-2005) and lung cancer incidence and mortality in North Carolina (2002-2006). Positive trends were observed between PM2.5 concentrations and lung cancer incidence and mortality; however, the R2 for both were <0.10. The slopes for the relationship between PM2.5 and lung cancer incidence and mortality were 1.26 (95% CI 0.31, 2.21, p-value 0.01) and 0.73 (95% CI 0.09, 1.36, p-value 0.03) per 1 μg/m3 PM2.5, respectively. These associations were slightly strengthened with the inclusion of variables representing socioeconomic status and smoking. Although variability is high, thus reflecting the importance of tobacco smoking and other etiologic agents that influence lung cancer incidence and mortality besides PM2.5, a positive trend is observed between PM2.5 and lung cancer incidence and mortality. 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subjects | Air Pollutants - adverse effects Air Pollutants - analysis Brief Report Ecology Environmental Exposure - analysis Female Humans Lung Neoplasms - epidemiology Lung Neoplasms - mortality Male North Carolina - epidemiology Particle Size Research Design |
title | An ecologic analysis of county-level PM2.5 concentrations and lung cancer incidence and mortality |
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