Loading…

An ecologic analysis of county-level PM2.5 concentrations and lung cancer incidence and mortality

Few studies have explored the relationship between PM2.5 and lung cancer incidence. Although results are mixed, some studies have demonstrated a positive relationship between PM2.5 and lung cancer mortality. Using an ecologic study design, we examined the county-level associations between PM2.5 conc...

Full description

Saved in:
Bibliographic Details
Published in:International journal of environmental research and public health 2011-06, Vol.8 (6), p.1865-1871
Main Authors: Vinikoor-Imler, Lisa C, Davis, J Allen, Luben, Thomas J
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c386t-3182bdce5f636c1d3cf98cc877cbb2378a66b6fed05a47cac488c99353fd1c263
cites cdi_FETCH-LOGICAL-c386t-3182bdce5f636c1d3cf98cc877cbb2378a66b6fed05a47cac488c99353fd1c263
container_end_page 1871
container_issue 6
container_start_page 1865
container_title International journal of environmental research and public health
container_volume 8
creator Vinikoor-Imler, Lisa C
Davis, J Allen
Luben, Thomas J
description Few studies have explored the relationship between PM2.5 and lung cancer incidence. Although results are mixed, some studies have demonstrated a positive relationship between PM2.5 and lung cancer mortality. Using an ecologic study design, we examined the county-level associations between PM2.5 concentrations (2002-2005) and lung cancer incidence and mortality in North Carolina (2002-2006). Positive trends were observed between PM2.5 concentrations and lung cancer incidence and mortality; however, the R2 for both were
doi_str_mv 10.3390/ijerph8061865
format article
fullrecord <record><control><sourceid>pubmed_cross</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3138001</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>21776206</sourcerecordid><originalsourceid>FETCH-LOGICAL-c386t-3182bdce5f636c1d3cf98cc877cbb2378a66b6fed05a47cac488c99353fd1c263</originalsourceid><addsrcrecordid>eNpVUMtOwzAQtBCIlsKRK_IPpNhxs3EuSFXFSyqCA5wjZ-O0rly7stNK-XsChao97WhmdnY1hNxyNhaiYPdmpcNmKRlwCdkZGXIAlkyA8fMjPCBXMa4YE3ICxSUZpDzPIWUwJGrqqEZv_cIgVU7ZLppIfUPRb13bJVbvtKUfb-k46ymH2rVBtca72LtrarduQVH1fKDGoal1D3-VtQ-tsqbtrslFo2zUN39zRL6eHj9nL8n8_fl1Np0nKCS0ieAyrWrUWQMCkNcCm0IiyjzHqkpFLhVABY2uWaYmOSqcSIlFITLR1BxTECPysM_dbKu1rvef2nITzFqFrvTKlKeKM8ty4Xel4EIyxvuAZB-AwccYdHPY5az86bo86br33x0fPLj_yxXfPaR-Vw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>An ecologic analysis of county-level PM2.5 concentrations and lung cancer incidence and mortality</title><source>Publicly Available Content Database</source><source>Full-Text Journals in Chemistry (Open access)</source><source>PubMed Central</source><creator>Vinikoor-Imler, Lisa C ; Davis, J Allen ; Luben, Thomas J</creator><creatorcontrib>Vinikoor-Imler, Lisa C ; Davis, J Allen ; Luben, Thomas J</creatorcontrib><description>Few studies have explored the relationship between PM2.5 and lung cancer incidence. Although results are mixed, some studies have demonstrated a positive relationship between PM2.5 and lung cancer mortality. Using an ecologic study design, we examined the county-level associations between PM2.5 concentrations (2002-2005) and lung cancer incidence and mortality in North Carolina (2002-2006). Positive trends were observed between PM2.5 concentrations and lung cancer incidence and mortality; however, the R2 for both were &lt;0.10. The slopes for the relationship between PM2.5 and lung cancer incidence and mortality were 1.26 (95% CI 0.31, 2.21, p-value 0.01) and 0.73 (95% CI 0.09, 1.36, p-value 0.03) per 1 μg/m3 PM2.5, respectively. These associations were slightly strengthened with the inclusion of variables representing socioeconomic status and smoking. Although variability is high, thus reflecting the importance of tobacco smoking and other etiologic agents that influence lung cancer incidence and mortality besides PM2.5, a positive trend is observed between PM2.5 and lung cancer incidence and mortality. This suggests the possibility of an association between PM2.5 concentrations and lung cancer incidence and mortality.</description><identifier>ISSN: 1660-4601</identifier><identifier>ISSN: 1661-7827</identifier><identifier>EISSN: 1660-4601</identifier><identifier>DOI: 10.3390/ijerph8061865</identifier><identifier>PMID: 21776206</identifier><language>eng</language><publisher>Switzerland: Molecular Diversity Preservation International (MDPI)</publisher><subject>Air Pollutants - adverse effects ; Air Pollutants - analysis ; Brief Report ; Ecology ; Environmental Exposure - analysis ; Female ; Humans ; Lung Neoplasms - epidemiology ; Lung Neoplasms - mortality ; Male ; North Carolina - epidemiology ; Particle Size ; Research Design</subject><ispartof>International journal of environmental research and public health, 2011-06, Vol.8 (6), p.1865-1871</ispartof><rights>2011 by US EPA; licensee MDPI, Basel, Switzerland 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-3182bdce5f636c1d3cf98cc877cbb2378a66b6fed05a47cac488c99353fd1c263</citedby><cites>FETCH-LOGICAL-c386t-3182bdce5f636c1d3cf98cc877cbb2378a66b6fed05a47cac488c99353fd1c263</cites><orcidid>0000-0002-7867-5126</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138001/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138001/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21776206$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vinikoor-Imler, Lisa C</creatorcontrib><creatorcontrib>Davis, J Allen</creatorcontrib><creatorcontrib>Luben, Thomas J</creatorcontrib><title>An ecologic analysis of county-level PM2.5 concentrations and lung cancer incidence and mortality</title><title>International journal of environmental research and public health</title><addtitle>Int J Environ Res Public Health</addtitle><description>Few studies have explored the relationship between PM2.5 and lung cancer incidence. Although results are mixed, some studies have demonstrated a positive relationship between PM2.5 and lung cancer mortality. Using an ecologic study design, we examined the county-level associations between PM2.5 concentrations (2002-2005) and lung cancer incidence and mortality in North Carolina (2002-2006). Positive trends were observed between PM2.5 concentrations and lung cancer incidence and mortality; however, the R2 for both were &lt;0.10. The slopes for the relationship between PM2.5 and lung cancer incidence and mortality were 1.26 (95% CI 0.31, 2.21, p-value 0.01) and 0.73 (95% CI 0.09, 1.36, p-value 0.03) per 1 μg/m3 PM2.5, respectively. These associations were slightly strengthened with the inclusion of variables representing socioeconomic status and smoking. Although variability is high, thus reflecting the importance of tobacco smoking and other etiologic agents that influence lung cancer incidence and mortality besides PM2.5, a positive trend is observed between PM2.5 and lung cancer incidence and mortality. This suggests the possibility of an association between PM2.5 concentrations and lung cancer incidence and mortality.</description><subject>Air Pollutants - adverse effects</subject><subject>Air Pollutants - analysis</subject><subject>Brief Report</subject><subject>Ecology</subject><subject>Environmental Exposure - analysis</subject><subject>Female</subject><subject>Humans</subject><subject>Lung Neoplasms - epidemiology</subject><subject>Lung Neoplasms - mortality</subject><subject>Male</subject><subject>North Carolina - epidemiology</subject><subject>Particle Size</subject><subject>Research Design</subject><issn>1660-4601</issn><issn>1661-7827</issn><issn>1660-4601</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNpVUMtOwzAQtBCIlsKRK_IPpNhxs3EuSFXFSyqCA5wjZ-O0rly7stNK-XsChao97WhmdnY1hNxyNhaiYPdmpcNmKRlwCdkZGXIAlkyA8fMjPCBXMa4YE3ICxSUZpDzPIWUwJGrqqEZv_cIgVU7ZLppIfUPRb13bJVbvtKUfb-k46ymH2rVBtca72LtrarduQVH1fKDGoal1D3-VtQ-tsqbtrslFo2zUN39zRL6eHj9nL8n8_fl1Np0nKCS0ieAyrWrUWQMCkNcCm0IiyjzHqkpFLhVABY2uWaYmOSqcSIlFITLR1BxTECPysM_dbKu1rvef2nITzFqFrvTKlKeKM8ty4Xel4EIyxvuAZB-AwccYdHPY5az86bo86br33x0fPLj_yxXfPaR-Vw</recordid><startdate>20110601</startdate><enddate>20110601</enddate><creator>Vinikoor-Imler, Lisa C</creator><creator>Davis, J Allen</creator><creator>Luben, Thomas J</creator><general>Molecular Diversity Preservation International (MDPI)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7867-5126</orcidid></search><sort><creationdate>20110601</creationdate><title>An ecologic analysis of county-level PM2.5 concentrations and lung cancer incidence and mortality</title><author>Vinikoor-Imler, Lisa C ; Davis, J Allen ; Luben, Thomas J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-3182bdce5f636c1d3cf98cc877cbb2378a66b6fed05a47cac488c99353fd1c263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Air Pollutants - adverse effects</topic><topic>Air Pollutants - analysis</topic><topic>Brief Report</topic><topic>Ecology</topic><topic>Environmental Exposure - analysis</topic><topic>Female</topic><topic>Humans</topic><topic>Lung Neoplasms - epidemiology</topic><topic>Lung Neoplasms - mortality</topic><topic>Male</topic><topic>North Carolina - epidemiology</topic><topic>Particle Size</topic><topic>Research Design</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vinikoor-Imler, Lisa C</creatorcontrib><creatorcontrib>Davis, J Allen</creatorcontrib><creatorcontrib>Luben, Thomas J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>International journal of environmental research and public health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vinikoor-Imler, Lisa C</au><au>Davis, J Allen</au><au>Luben, Thomas J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An ecologic analysis of county-level PM2.5 concentrations and lung cancer incidence and mortality</atitle><jtitle>International journal of environmental research and public health</jtitle><addtitle>Int J Environ Res Public Health</addtitle><date>2011-06-01</date><risdate>2011</risdate><volume>8</volume><issue>6</issue><spage>1865</spage><epage>1871</epage><pages>1865-1871</pages><issn>1660-4601</issn><issn>1661-7827</issn><eissn>1660-4601</eissn><abstract>Few studies have explored the relationship between PM2.5 and lung cancer incidence. Although results are mixed, some studies have demonstrated a positive relationship between PM2.5 and lung cancer mortality. Using an ecologic study design, we examined the county-level associations between PM2.5 concentrations (2002-2005) and lung cancer incidence and mortality in North Carolina (2002-2006). Positive trends were observed between PM2.5 concentrations and lung cancer incidence and mortality; however, the R2 for both were &lt;0.10. The slopes for the relationship between PM2.5 and lung cancer incidence and mortality were 1.26 (95% CI 0.31, 2.21, p-value 0.01) and 0.73 (95% CI 0.09, 1.36, p-value 0.03) per 1 μg/m3 PM2.5, respectively. These associations were slightly strengthened with the inclusion of variables representing socioeconomic status and smoking. Although variability is high, thus reflecting the importance of tobacco smoking and other etiologic agents that influence lung cancer incidence and mortality besides PM2.5, a positive trend is observed between PM2.5 and lung cancer incidence and mortality. This suggests the possibility of an association between PM2.5 concentrations and lung cancer incidence and mortality.</abstract><cop>Switzerland</cop><pub>Molecular Diversity Preservation International (MDPI)</pub><pmid>21776206</pmid><doi>10.3390/ijerph8061865</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-7867-5126</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1660-4601
ispartof International journal of environmental research and public health, 2011-06, Vol.8 (6), p.1865-1871
issn 1660-4601
1661-7827
1660-4601
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3138001
source Publicly Available Content Database; Full-Text Journals in Chemistry (Open access); PubMed Central
subjects Air Pollutants - adverse effects
Air Pollutants - analysis
Brief Report
Ecology
Environmental Exposure - analysis
Female
Humans
Lung Neoplasms - epidemiology
Lung Neoplasms - mortality
Male
North Carolina - epidemiology
Particle Size
Research Design
title An ecologic analysis of county-level PM2.5 concentrations and lung cancer incidence and mortality
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T22%3A20%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubmed_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=An%20ecologic%20analysis%20of%20county-level%20PM2.5%20concentrations%20and%20lung%20cancer%20incidence%20and%20mortality&rft.jtitle=International%20journal%20of%20environmental%20research%20and%20public%20health&rft.au=Vinikoor-Imler,%20Lisa%20C&rft.date=2011-06-01&rft.volume=8&rft.issue=6&rft.spage=1865&rft.epage=1871&rft.pages=1865-1871&rft.issn=1660-4601&rft.eissn=1660-4601&rft_id=info:doi/10.3390/ijerph8061865&rft_dat=%3Cpubmed_cross%3E21776206%3C/pubmed_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c386t-3182bdce5f636c1d3cf98cc877cbb2378a66b6fed05a47cac488c99353fd1c263%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/21776206&rfr_iscdi=true